5T0K

Structure of G9a SET-domain with H3K9M mutant peptide and SAM

Summary for 5T0K

• Entry DOI: 10.2210/pdb5t0k/pdb
• Related: 5T0M
• Descriptor: Histone-lysine N-methyltransferase EHMT2, H3K9 mutant peptide, ZINC ION, ... (5 entities in total)
• Functional Keywords: histone methyltransferase, set domain, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 69377.37

Authors

Xu, K.,Tong, L. (deposition date: 2016-08-16, release date: 2016-10-05, Last modification date: 2023-10-04)

• Primary citation: Shan, C.M.,Wang, J.,Xu, K.,Chen, H.,Yue, J.X.,Andrews, S.,Moresco, J.J.,Yates, J.R.,Nagy, P.L.,Tong, L.,Jia, S.; A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading.; Elife, 5:-, 2016; PubMed: 27648579; DOI: 10.7554/eLife.17903

Experimental method

X-RAY DIFFRACTION (1.7 Å)