5Z0V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z0v by Molmil](/molmil-images/mine/5z0v) | Structural insight into the Zika virus capsid encapsulating the viral genome | 分子名称: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | 登録日 | 2017-12-21 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.913 Å) | 主引用文献 | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
|
|
4MP2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mp2 by Molmil](/molmil-images/mine/4mp2) | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA1 | 分子名称: | (5-bromo-2,4-dihydroxyphenyl)(1,3-dihydro-2H-isoindol-2-yl)methanone, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | 登録日 | 2013-09-12 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.751 Å) | 主引用文献 | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket. J.Biol.Chem., 289, 2014
|
|
4MP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mp7 by Molmil](/molmil-images/mine/4mp7) | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PA7 | 分子名称: | 4-(1,3-dihydro-2H-isoindol-2-ylcarbonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | 登録日 | 2013-09-12 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket. J.Biol.Chem., 289, 2014
|
|
4MPE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mpe by Molmil](/molmil-images/mine/4mpe) | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS8 | 分子名称: | 4-[(5-hydroxy-1,3-dihydro-2H-isoindol-2-yl)sulfonyl]benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | 登録日 | 2013-09-12 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.953 Å) | 主引用文献 | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket. J.Biol.Chem., 289, 2014
|
|
4MPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mpc by Molmil](/molmil-images/mine/4mpc) | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS2 | 分子名称: | 4-(isoindolin-2-ylsulfonyl)benzene-1,3-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | 著者 | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | 登録日 | 2013-09-12 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.699 Å) | 主引用文献 | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket. J.Biol.Chem., 289, 2014
|
|
4LFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lfu by Molmil](/molmil-images/mine/4lfu) | Crystal structure of Escherichia coli SdiA in the space group C2 | 分子名称: | CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL | 著者 | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | 登録日 | 2013-06-27 | 公開日 | 2014-03-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor Acta Crystallogr.,Sect.D, 70, 2014
|
|
4LGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lgw by Molmil](/molmil-images/mine/4lgw) | Crystal structure of Escherichia coli SdiA in the space group P6522 | 分子名称: | GLYCEROL, Regulatory protein SdiA | 著者 | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | 登録日 | 2013-06-28 | 公開日 | 2014-03-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor Acta Crystallogr.,Sect.D, 70, 2014
|
|
5Z0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z0r by Molmil](/molmil-images/mine/5z0r) | Structural insight into the Zika virus capsid encapsulating the viral genome | 分子名称: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | 登録日 | 2017-12-20 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural insight into the Zika virus capsid encapsulating the viral genome. Cell Res., 28, 2018
|
|
2JSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jss by Molmil](/molmil-images/mine/2jss) | NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B | 分子名称: | Chimera of Histone H2B.1 and Histone H2A.Z, Uncharacterized protein YER030W | 著者 | Zhou, Z, Feng, H, Hansen, D.F, Kato, H, Luk, E, Freedberg, D.I, Kay, L.E, Wu, C, Bai, Y. | 登録日 | 2007-07-11 | 公開日 | 2008-05-20 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B. Nat.Struct.Mol.Biol., 15, 2008
|
|
7CIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ciw by Molmil](/molmil-images/mine/7ciw) | |
7CNN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cnn by Molmil](/molmil-images/mine/7cnn) | vinorelbine in complex with tubulin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
|
|
2GOF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gof by Molmil](/molmil-images/mine/2gof) | Three-dimensional structure of the trans-membrane domain of Vpu from HIV-1 in aligned phospholipid bicelles | 分子名称: | VPU protein | 著者 | Park, S.H, De Angelis, A.A, Nevzorov, A.A, Wu, C.H, Opella, S.J. | 登録日 | 2006-04-12 | 公開日 | 2006-08-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-Dimensional Structure of the Transmembrane Domain of Vpu from HIV-1 in Aligned Phospholipid Bicelles. Biophys.J., 91, 2006
|
|
2LAS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2las by Molmil](/molmil-images/mine/2las) | Molecular Determinants of Paralogue-Specific SUMO-SIM Recognition | 分子名称: | M-IR2_peptide, Small ubiquitin-related modifier 1 | 著者 | Namanja, A, Li, Y, Su, Y, Wong, S, Lu, J, Colson, L, Wu, C, Li, S, Chen, Y. | 登録日 | 2011-03-20 | 公開日 | 2011-12-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Insights into High Affinity Small Ubiquitin-like Modifier (SUMO) Recognition by SUMO-interacting Motifs (SIMs) Revealed by a Combination of NMR and Peptide Array Analysis. J.Biol.Chem., 287, 2012
|
|
2L5A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l5a by Molmil](/molmil-images/mine/2l5a) | Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3 | 分子名称: | Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4 | 著者 | Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y. | 登録日 | 2010-10-28 | 公開日 | 2011-03-16 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3. Nature, 472, 2011
|
|
7YDX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ydx by Molmil](/molmil-images/mine/7ydx) | Crystal structure of human RIPK1 kinase domain in complex with compound RI-962 | 分子名称: | 1-methyl-5-[2-(2-methylpropanoylamino)-[1,2,4]triazolo[1,5-a]pyridin-7-yl]-N-[(1S)-1-phenylethyl]indole-3-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Zhang, L, Wang, Y, Li, Y, Wu, C, Luo, X, Wang, T, Lei, J, Yang, S. | 登録日 | 2022-07-04 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.642 Å) | 主引用文献 | Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor. Nat Commun, 13, 2022
|
|
7CNM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7cnm by Molmil](/molmil-images/mine/7cnm) | YDX in complex with tubulin | 分子名称: | (2~{S},4~{S})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-4-methyl-3-[[(2~{S},3~{S})-3-methyl-2-[[(2~{R})-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-cyclohexyl-2-methyl-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, Y.X, Wu, C.Y. | 登録日 | 2020-08-02 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | The high-resolution X-ray structure of vinca-domain inhibitors of microtubules provides a rational approach for drug design. Febs Lett., 595, 2021
|
|
7V66
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7v66 by Molmil](/molmil-images/mine/7v66) | Structure of Apoferritin | 分子名称: | Ferritin heavy chain | 著者 | Zhang, X, Wu, C, Shi, H. | 登録日 | 2021-08-19 | 公開日 | 2022-10-05 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (1.89 Å) | 主引用文献 | Low-cooling-rate freezing in biomolecular cryo-electron microscopy for recovery of initial frames. QRB Discov, 2, 2021
|
|
6IMG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6img by Molmil](/molmil-images/mine/6img) | Solution Structure of Bicyclic Peptide pb-13 | 分子名称: | (ACE)-GLY-CYS-PRO-CYS-ILE-TRP-PRO-GLU-LEU-CYS-PRO-TRP-ILE-ARG-SER-CYS-(NH2) | 著者 | Yao, H, Lin, P, Zha, J, Zha, M, Zhao, Y, Wu, C. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 実験手法 | SOLUTION NMR | 主引用文献 | Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns. Chembiochem, 20, 2019
|
|
6IMH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6imh by Molmil](/molmil-images/mine/6imh) | Solution Structure of Bicyclic Peptide pb-18 | 分子名称: | (ACE)-GLY-CYS-PRO-CYS-GLU-PRO-SER-TYR-LEU-CYS-PRO-TRP-LEU-PRO-GLY-CYS-(NH2) | 著者 | Yao, H, Lin, P, Zha, J, Zha, M, Zhao, Y, Wu, C. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 実験手法 | SOLUTION NMR | 主引用文献 | Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns. Chembiochem, 20, 2019
|
|
7XGD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xgd by Molmil](/molmil-images/mine/7xgd) | |
4LC7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lc7 by Molmil](/molmil-images/mine/4lc7) | Aminooxazoline inhibitor of BACE-1 | 分子名称: | (3aR,7aR)-3a-[3-(5-chloropyridin-3-yl)phenyl]-3a,4,5,6,7,7a-hexahydro-1,3-benzoxazol-2-amine, Beta-Secretase-1, NICKEL (II) ION | 著者 | Huestis, M.P, Liu, W, Volgraf, M, Purkey, H.E, Wu, C, Wang, W, Smith, D, Vigers, G.P.A, Dutcher, D, Hunt, K.W, Siu, M. | 登録日 | 2013-06-21 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Diethylaminosulfur Trifluoride-Mediated Intramolecular Cyclization of 2-hydroxycycloalkylureas to Fused Bicyclic Aminooxazoline Compounds and Evaluation of Their Biochemical Activity Against β-Secretase-1 (BACE-1) Tetrahedron Lett., 2013
|
|
7YIM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7yim by Molmil](/molmil-images/mine/7yim) | Cryo-EM structure of human Alpha-fetoprotein | 分子名称: | Alpha-fetoprotein | 著者 | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | 登録日 | 2022-07-17 | 公開日 | 2023-01-18 | 最終更新日 | 2023-01-25 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
|
|
7XQX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xqx by Molmil](/molmil-images/mine/7xqx) | Crystal structure of T2R-TTL-27a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-7-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Crystal structure of T2R-TT complex To Be Published
|
|
7XR1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xr1 by Molmil](/molmil-images/mine/7xr1) | Crystal structure of T2R-TTL-3a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-6-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Crystal structure of T2R-TTL-3a complex To Be Published
|
|
7XR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xr0 by Molmil](/molmil-images/mine/7xr0) | Crystal structure of T2R-TTL-27a complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloranyl-5-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine, CALCIUM ION, ... | 著者 | Lun, T, Wu, C.Y. | 登録日 | 2022-05-09 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of T2R-TTL-27a complex To Be Published
|
|