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PDB: 979 results

8TZ5
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BU of 8tz5 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ9
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BU of 8tz9 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT2-INT2 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ2
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BU of 8tz2 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in MSP2N2 nanodiscs, apo state
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZD
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BU of 8tzd by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ6
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BU of 8tz6 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ3
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BU of 8tz3 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ7
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BU of 8tz7 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT1 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZA
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BU of 8tza by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
Descriptor: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ8
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BU of 8tz8 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ1
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BU of 8tz1 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Ribavirin
Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, ...
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
6OB6
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BU of 6ob6 by Molmil
Human equilibrative nucleoside transporter-1, S-(4-nitrobenzyl)-6-thioinosine bound, merohedrally twinned
Descriptor: 6-{[(4-nitrophenyl)methyl]sulfanyl}-9-beta-D-ribofuranosyl-9H-purine, Equilibrative nucleoside transporter 1
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2019-03-19
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of human ENT1 in complex with adenosine reuptake inhibitors.
Nat.Struct.Mol.Biol., 26, 2019
6OB7
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BU of 6ob7 by Molmil
Human equilibrative nucleoside transporter-1, dilazep bound
Descriptor: (1,4-diazepane-1,4-diyl)di(propane-3,1-diyl) bis(3,4,5-trimethoxybenzoate), (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Equilibrative nucleoside transporter 1
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2019-03-19
Release date:2019-07-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of human ENT1 in complex with adenosine reuptake inhibitors.
Nat.Struct.Mol.Biol., 26, 2019
8DEP
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BU of 8dep by Molmil
Cryo-EM structure of the human reduced folate carrier, apo condition
Descriptor: Digitonin, Reduced folate transporter,Soluble cytochrome b562
Authors:Wright, N.J, Fedor, J.G, Lee, S.-Y.
Deposit date:2022-06-21
Release date:2022-09-21
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Methotrexate recognition by the human reduced folate carrier SLC19A1.
Nature, 609, 2022
8TZ4
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BU of 8tz4 by Molmil
Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
Authors:Wright, N.J, Lee, S.-Y.
Deposit date:2023-08-26
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
7TX7
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BU of 7tx7 by Molmil
Cryo-EM structure of the human reduced folate carrier
Descriptor: Digitonin, Reduced folate transporter,Soluble cytochrome b562
Authors:Wright, N.J, Fedor, J.G, Lee, S.-Y.
Deposit date:2022-02-07
Release date:2022-09-21
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Methotrexate recognition by the human reduced folate carrier SLC19A1.
Nature, 609, 2022
7TX6
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BU of 7tx6 by Molmil
Cryo-EM structure of the human reduced folate carrier in complex with methotrexate
Descriptor: Digitonin, METHOTREXATE, Reduced folate transporter,Soluble cytochrome b562
Authors:Wright, N.J, Fedor, J.G, Lee, S.-Y.
Deposit date:2022-02-07
Release date:2022-09-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Methotrexate recognition by the human reduced folate carrier SLC19A1.
Nature, 609, 2022
4RSV
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BU of 4rsv by Molmil
Human Obscurin Ig58 Domain
Descriptor: Obscurin
Authors:Wright, N.T, Oehler, M.C, Berndsen, C.E, Du Pont, K.E.
Deposit date:2014-11-11
Release date:2016-02-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Arrhythmia and deregulated Ca2+ cycling underlie the development of hypertrophic cardiomyopathy due to mutant giant obscurin
To be Published
6MG9
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BU of 6mg9 by Molmil
Human Obscurin Ig57 Domain
Descriptor: Obscurin
Authors:Wright, N.T, Whitley, J.A.
Deposit date:2018-09-13
Release date:2019-02-06
Last modified:2019-11-27
Method:SOLUTION NMR
Cite:Obscurin is a semi-flexible molecule in solution.
Protein Sci., 28, 2019
6DL4
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BU of 6dl4 by Molmil
Human Titin ZIg10
Descriptor: Titin
Authors:Wright, N.T.
Deposit date:2018-05-31
Release date:2019-08-21
Last modified:2020-03-04
Method:SOLUTION NMR
Cite:Structural Insights on the Obscurin-Binding Domains in Titin.
Protein Pept.Lett., 25, 2018
2MWC
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BU of 2mwc by Molmil
Solution structure of human obscurin Ig58
Descriptor: Obscurin
Authors:Wright, N.T, Meyer, L.C.
Deposit date:2014-11-03
Release date:2015-12-09
Method:SOLUTION NMR
Cite:Obscurin Ig58-Ig59 causes malformed muscle structure
To be Published
2N56
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BU of 2n56 by Molmil
Ig59 domain of human obscurin A
Descriptor: Obscurin
Authors:Wright, N.T, Caldwell, T.A.
Deposit date:2015-07-08
Release date:2016-07-13
Method:SOLUTION NMR
Cite:Identification and characterization of disease-causing obscurin mutations
To be Published
1ZFS
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BU of 1zfs by Molmil
Solution structure of S100A1 bound to calcium
Descriptor: CALCIUM ION, S-100 protein, alpha chain
Authors:Wright, N.T, Varney, K.M, Weber, D.J.
Deposit date:2005-04-20
Release date:2006-04-11
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The three-dimensional solution structure of Ca(2+)-bound S100A1 as determined by NMR spectroscopy
J.Mol.Biol., 353, 2006
1ZRI
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BU of 1zri by Molmil
NOE-based solution structure with dipolar coupling restraints of rat OMP (olfactory marker protein)
Descriptor: Olfactory marker protein
Authors:Wright, N.T, Margolis, J.W, Margolis, F.M, Weber, D.J.
Deposit date:2005-05-19
Release date:2006-05-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:LRefinement of the Solution Structure of Rat Olfactory Marker Protein (OMP)
J.BIOMOL.NMR, 33, 2005
5TZM
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BU of 5tzm by Molmil
59th Ig domain of human obscurin (OBSCN Ig59)
Descriptor: Obscurin
Authors:Wright, N.T, Berndsen, C.E, Policke, R.A.
Deposit date:2016-11-21
Release date:2017-11-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.177 Å)
Cite:A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.
PLoS ONE, 12, 2017
2K7O
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BU of 2k7o by Molmil
Ca2+-S100B, refined with RDCs
Descriptor: CALCIUM ION, Protein S100-B
Authors:Wright, N.T, Inman, K.G, Levine, J.A, Weber, D.J.
Deposit date:2008-08-17
Release date:2008-11-18
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B.
J.Biomol.Nmr, 42, 2008

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PDB entries from 2024-04-24

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