4RSV
Human Obscurin Ig58 Domain
Summary for 4RSV
Entry DOI | 10.2210/pdb4rsv/pdb |
Related | 2MWC |
Descriptor | Obscurin (2 entities in total) |
Functional Keywords | ig-like, cytoskeletal, titin, myocytes, structural protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 3: Cytoplasm, myofibril, sarcomere, M line : Q5VST9 |
Total number of polymer chains | 1 |
Total formula weight | 11423.82 |
Authors | Wright, N.T.,Oehler, M.C.,Berndsen, C.E.,Du Pont, K.E. (deposition date: 2014-11-11, release date: 2016-02-24, Last modification date: 2023-09-20) |
Primary citation | Hu, L.Y.R.,Ackermann, M.A.,Hecker, P.A.,Prosser, B.L.,King, B.,O'Connell, K.A.,Asico, L.D.,Jose, P.A.,Wright, N.T.,Oehler, M.C.,Berndsen, C.E.,Du Pont, K.E.,Meyer, L.C.,Lederer, W.J.,Kontrogianni-Konstantopoulos, A. Arrhythmia and deregulated Ca2+ cycling underlie the development of hypertrophic cardiomyopathy due to mutant giant obscurin To be Published, |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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