6KH5
| Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | Descriptor: | FE (III) ION, Ferritin, NICKEL (II) ION | Authors: | Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G. | Deposit date: | 2019-07-12 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.294 Å) | Cite: | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes. Chemistry, 26, 2020
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3NCO
| Crystal structure of FnCel5A from F. nodosum Rt17-B1 | Descriptor: | Endoglucanase FnCel5A, PHOSPHATE ION, peptide (ALA)(ASN)(GLU), ... | Authors: | Zheng, B.S, Yang, W, Wang, Y, Lou, Z.Y, Rao, Z.H, Feng, Y. | Deposit date: | 2010-06-05 | Release date: | 2011-06-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of FnCel5A from F. nodosum Rt17-B1 To be Published
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7D7E
| Structure of PKD1L3-CTD/PKD2L1 in apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ... | Authors: | Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y. | Deposit date: | 2020-10-03 | Release date: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel. Nat Commun, 12, 2021
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6IFO
| Crystal structure of AcrIIA2-SpyCas9-sgRNA ternary complex | Descriptor: | AcrIIA2, CRISPR-associated endonuclease Cas9/Csn1, RNA (99-MER) | Authors: | Liu, L, Wang, Y. | Deposit date: | 2018-09-20 | Release date: | 2019-01-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.313 Å) | Cite: | Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race. Mol. Cell, 73, 2019
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6IPQ
| Non-native ferritin 8-mer mutant-C90A/C102A/C130A | Descriptor: | Ferritin heavy chain, MAGNESIUM ION | Authors: | Zang, J, Chen, H, Wang, Y, Zhao, G. | Deposit date: | 2018-11-03 | Release date: | 2019-03-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.103 Å) | Cite: | Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages. Nat Commun, 10, 2019
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6KH1
| Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes | Descriptor: | FE (III) ION, Ferritin, NICKEL (II) ION | Authors: | Gu, C, Chen, H, Wang, Y, Zhang, T, Whang, H, Zhao, G. | Deposit date: | 2019-07-12 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes. Chemistry, 26, 2020
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7BXG
| MavC-UBE2N-Ub complex | Descriptor: | MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N | Authors: | Gao, P, Wang, Y. | Deposit date: | 2020-04-19 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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7BXH
| MavC-Lpg2149 complex | Descriptor: | Lpg2149, MavC | Authors: | Gao, P, Wang, Y. | Deposit date: | 2020-04-19 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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8TG1
| Caldicellulosiruptor saccharolyticus periplasmic urea-binding protein | Descriptor: | BROMIDE ION, Extracellular ligand-binding receptor, UREA | Authors: | Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W. | Deposit date: | 2023-07-12 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Structure-based functional analysis reveals multiple roles and widespread use of urea-binding proteins in nitrogen metabolism To Be Published
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8WLJ
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8WLL
| Cryo-EM structure of human VMAT2 Y422C, in the presence of reserpine, determined in an inward-facing conformation | Descriptor: | Synaptic vesicular amine transporter, reserpine | Authors: | Qu, Q, Wang, Y, Zhou, Z. | Deposit date: | 2023-09-30 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | Cryo-EM structure of human VMAT2 Y422C, in the presence of reserpine, determined in an inward-facing conformation To Be Published
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8WLK
| Cryo-EM structure of human VMAT2 in presence of Tetrabenazine, determined in an outward-facing conformation | Descriptor: | (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, Synaptic vesicular amine transporter | Authors: | Qu, Q, Wang, Y, Zhou, Z. | Deposit date: | 2023-09-30 | Release date: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Cryo-EM structure of human apo VMAT2 in an outward-facing conformation To Be Published
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7D6H
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8WLM
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2MVW
| Solution structure of the TRIM19 B-box1 (B1) of human promyelocytic leukemia (PML) | Descriptor: | Protein PML, ZINC ION | Authors: | Huang, S, Naik, M.T, Fan, P, Wang, Y, Chang, C, Huang, T. | Deposit date: | 2014-10-17 | Release date: | 2014-11-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The B-box 1 dimer of human promyelocytic leukemia protein. J.Biomol.Nmr, 60, 2014
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6AGK
| The structure of CH-II-77-tubulin complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Chen, H, Arnst, K, Wang, Y, Miller, D, Li, W. | Deposit date: | 2018-08-13 | Release date: | 2019-08-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties. J.Med.Chem., 63, 2020
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8WRB
| Lysophosphatidylserine receptor GPR34-Gi complex | Descriptor: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Gong, W, Liu, G, Li, X, Wang, Y, Zhang, X. | Deposit date: | 2023-10-13 | Release date: | 2023-11-08 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174. Plos Biol., 21, 2023
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7E35
| Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43 | Descriptor: | N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Non-structural protein 3, ZINC ION | Authors: | Liu, J, Wang, Y, Xu, X, Pan, L. | Deposit date: | 2021-02-08 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chem Biol, 28, 2021
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6LP2
| Structure of Lpg2148/UBE2N-Ub complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 N, Uncharacterized protein lpg2148 | Authors: | Feng, Y, Wang, Y, Huang, Y, Li, D. | Deposit date: | 2020-01-08 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.479 Å) | Cite: | Structure of Lpg2148/UBE2N-Ub complex To Be Published
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6LW4
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6BR1
| Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 4a | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)pyrido[2,3-d]pyrimidine, CALCIUM ION, ... | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | Deposit date: | 2017-11-29 | Release date: | 2018-06-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. J. Med. Chem., 61, 2018
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6BS2
| Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 8b | Descriptor: | 1-(3,6-dimethyl[1,2]oxazolo[5,4-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | Deposit date: | 2017-12-01 | Release date: | 2018-06-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. J. Med. Chem., 61, 2018
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2LK3
| U2/U6 Helix I | Descriptor: | RNA (5'-R(*GP*GP*CP*UP*UP*AP*GP*AP*UP*CP*AP*GP*AP*AP*AP*UP*GP*AP*UP*CP*AP*GP*CP*C)-3') | Authors: | Burke, J.E, Sashital, D.G, Zuo, X.E, Wang, Y, Butcher, S.E. | Deposit date: | 2011-10-03 | Release date: | 2012-02-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the yeast U2/U6 snRNA complex. Rna, 18, 2012
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2LKR
| Yeast U2/U6 complex | Descriptor: | RNA (111-MER) | Authors: | Burke, J.E, Sashital, D.G, Zuo, X, Wang, Y, Butcher, S.E. | Deposit date: | 2011-10-19 | Release date: | 2012-02-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of the yeast U2/U6 snRNA complex. Rna, 18, 2012
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7WDL
| Fungal immunomodulatory protein FIP-nha | Descriptor: | Fungal immunomodulatory protein | Authors: | Liu, Y, Bastiaan-Net, S, Zhang, Y, Hoppenbrouwers, T, Xie, Y, Wang, Y, Wei, X, Du, G, Zhang, H, Imam, K.M.S.U, Wichers, H.J, Li, Z. | Deposit date: | 2021-12-22 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Linking the thermostability of FIP-nha (Nectria haematococca) to its structural properties. Int.J.Biol.Macromol., 213, 2022
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