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PDB: 934 件

6KH5
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Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes
分子名称: FE (III) ION, Ferritin, NICKEL (II) ION
著者Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G.
登録日2019-07-12
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.294 Å)
主引用文献Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
3NCO
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BU of 3nco by Molmil
Crystal structure of FnCel5A from F. nodosum Rt17-B1
分子名称: Endoglucanase FnCel5A, PHOSPHATE ION, peptide (ALA)(ASN)(GLU), ...
著者Zheng, B.S, Yang, W, Wang, Y, Lou, Z.Y, Rao, Z.H, Feng, Y.
登録日2010-06-05
公開日2011-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of FnCel5A from F. nodosum Rt17-B1
To be Published
7D7E
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BU of 7d7e by Molmil
Structure of PKD1L3-CTD/PKD2L1 in apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Polycystic kidney disease 2-like 1 protein, ...
著者Su, Q, Chen, M, Li, B, Wang, Y, Jing, D, Zhan, X, Yu, Y, Shi, Y.
登録日2020-10-03
公開日2021-08-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for Ca 2+ activation of the heteromeric PKD1L3/PKD2L1 channel.
Nat Commun, 12, 2021
6IFO
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Crystal structure of AcrIIA2-SpyCas9-sgRNA ternary complex
分子名称: AcrIIA2, CRISPR-associated endonuclease Cas9/Csn1, RNA (99-MER)
著者Liu, L, Wang, Y.
登録日2018-09-20
公開日2019-01-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.313 Å)
主引用文献Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race.
Mol. Cell, 73, 2019
6IPQ
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Non-native ferritin 8-mer mutant-C90A/C102A/C130A
分子名称: Ferritin heavy chain, MAGNESIUM ION
著者Zang, J, Chen, H, Wang, Y, Zhao, G.
登録日2018-11-03
公開日2019-03-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages.
Nat Commun, 10, 2019
6KH1
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Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes
分子名称: FE (III) ION, Ferritin, NICKEL (II) ION
著者Gu, C, Chen, H, Wang, Y, Zhang, T, Whang, H, Zhao, G.
登録日2019-07-12
公開日2020-01-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
7BXG
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MavC-UBE2N-Ub complex
分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N
著者Gao, P, Wang, Y.
登録日2020-04-19
公開日2020-05-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
7BXH
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MavC-Lpg2149 complex
分子名称: Lpg2149, MavC
著者Gao, P, Wang, Y.
登録日2020-04-19
公開日2020-05-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
8TG1
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Caldicellulosiruptor saccharolyticus periplasmic urea-binding protein
分子名称: BROMIDE ION, Extracellular ligand-binding receptor, UREA
著者Allert, M.J, Kumar, S, Wang, Y, Beese, L.S, Hellinga, H.W.
登録日2023-07-12
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Structure-based functional analysis reveals multiple roles and widespread use of urea-binding proteins in nitrogen metabolism
To Be Published
8WLJ
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Cryo-EM structure of human apo VMAT2 with nanobody in an outward-facing conformation
分子名称: Synaptic vesicular amine transporter, nanobody
著者Qu, Q, Wang, Y, Zhou, Z.
登録日2023-09-30
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structure of human apo VMAT2 in an outward-facing conformation
To Be Published
8WLL
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Cryo-EM structure of human VMAT2 Y422C, in the presence of reserpine, determined in an inward-facing conformation
分子名称: Synaptic vesicular amine transporter, reserpine
著者Qu, Q, Wang, Y, Zhou, Z.
登録日2023-09-30
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Cryo-EM structure of human VMAT2 Y422C, in the presence of reserpine, determined in an inward-facing conformation
To Be Published
8WLK
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Cryo-EM structure of human VMAT2 in presence of Tetrabenazine, determined in an outward-facing conformation
分子名称: (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, Synaptic vesicular amine transporter
著者Qu, Q, Wang, Y, Zhou, Z.
登録日2023-09-30
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Cryo-EM structure of human apo VMAT2 in an outward-facing conformation
To Be Published
7D6H
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Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
分子名称: PHOSPHATE ION, Papain-like protease, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2020-09-30
公開日2020-11-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
8WLM
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Cryo-EM structure of human VMAT2 in presence of 5-HT, determined in an outward-facing conformation
分子名称: SEROTONIN, Synaptic vesicular amine transporter
著者Qu, Q, Wang, Y, Zhou, Z.
登録日2023-09-30
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Cryo-EM structure of human VMAT2 in presence of 5-HT in an outward-facing conformation
To Be Published
2MVW
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BU of 2mvw by Molmil
Solution structure of the TRIM19 B-box1 (B1) of human promyelocytic leukemia (PML)
分子名称: Protein PML, ZINC ION
著者Huang, S, Naik, M.T, Fan, P, Wang, Y, Chang, C, Huang, T.
登録日2014-10-17
公開日2014-11-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The B-box 1 dimer of human promyelocytic leukemia protein.
J.Biomol.Nmr, 60, 2014
6AGK
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BU of 6agk by Molmil
The structure of CH-II-77-tubulin complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Chen, H, Arnst, K, Wang, Y, Miller, D, Li, W.
登録日2018-08-13
公開日2019-08-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.
J.Med.Chem., 63, 2020
8WRB
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BU of 8wrb by Molmil
Lysophosphatidylserine receptor GPR34-Gi complex
分子名称: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Gong, W, Liu, G, Li, X, Wang, Y, Zhang, X.
登録日2023-10-13
公開日2023-11-08
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174.
Plos Biol., 21, 2023
7E35
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BU of 7e35 by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43
分子名称: N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Non-structural protein 3, ZINC ION
著者Liu, J, Wang, Y, Xu, X, Pan, L.
登録日2021-02-08
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
6LP2
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BU of 6lp2 by Molmil
Structure of Lpg2148/UBE2N-Ub complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 N, Uncharacterized protein lpg2148
著者Feng, Y, Wang, Y, Huang, Y, Li, D.
登録日2020-01-08
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.479 Å)
主引用文献Structure of Lpg2148/UBE2N-Ub complex
To Be Published
6LW4
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Structure of Lpg2148/Lpg2149 complex
分子名称: Uncharacterized protein Lpg2148, Uncharacterized protein Lpg2149
著者Feng, Y, Wang, Y, Huang, Y, Li, D.
登録日2020-02-07
公開日2021-02-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of Lpg2148/Lpg2149 complex
To Be Published
6BR1
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Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 4a
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-chloro-4-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)pyrido[2,3-d]pyrimidine, CALCIUM ION, ...
著者Kumar, G, Wang, Y, Li, W, White, S.W.
登録日2017-11-29
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
J. Med. Chem., 61, 2018
6BS2
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BU of 6bs2 by Molmil
Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 8b
分子名称: 1-(3,6-dimethyl[1,2]oxazolo[5,4-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Kumar, G, Wang, Y, Li, W, White, S.W.
登録日2017-12-01
公開日2018-06-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
J. Med. Chem., 61, 2018
2LK3
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U2/U6 Helix I
分子名称: RNA (5'-R(*GP*GP*CP*UP*UP*AP*GP*AP*UP*CP*AP*GP*AP*AP*AP*UP*GP*AP*UP*CP*AP*GP*CP*C)-3')
著者Burke, J.E, Sashital, D.G, Zuo, X.E, Wang, Y, Butcher, S.E.
登録日2011-10-03
公開日2012-02-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the yeast U2/U6 snRNA complex.
Rna, 18, 2012
2LKR
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Yeast U2/U6 complex
分子名称: RNA (111-MER)
著者Burke, J.E, Sashital, D.G, Zuo, X, Wang, Y, Butcher, S.E.
登録日2011-10-19
公開日2012-02-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the yeast U2/U6 snRNA complex.
Rna, 18, 2012
7WDL
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BU of 7wdl by Molmil
Fungal immunomodulatory protein FIP-nha
分子名称: Fungal immunomodulatory protein
著者Liu, Y, Bastiaan-Net, S, Zhang, Y, Hoppenbrouwers, T, Xie, Y, Wang, Y, Wei, X, Du, G, Zhang, H, Imam, K.M.S.U, Wichers, H.J, Li, Z.
登録日2021-12-22
公開日2022-06-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Linking the thermostability of FIP-nha (Nectria haematococca) to its structural properties.
Int.J.Biol.Macromol., 213, 2022

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件を2024-08-07に公開中

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