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PDB: 409 件

2HHI
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The solution structure of antigen MPT64 from Mycobacterium tuberculosis defines a novel class of beta-grasp proteins
分子名称: Immunogenic protein MPT64
著者Wang, Z, Potter, B.M, Gray, A.M, Sacksteder, K.A, Geisbrecht, B.V, Laity, J.H.
登録日2006-06-28
公開日2006-12-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The Solution Structure of Antigen MPT64 from Mycobacterium tuberculosis Defines a New Family of Beta-Grasp Proteins.
J.Mol.Biol., 366, 2007
1BMK
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655
分子名称: 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1A9U
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580
分子名称: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, MAP KINASE P38
著者Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-04-10
公開日1999-04-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL6
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995
分子名称: 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-11
公開日1999-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL7
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025
分子名称: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
7KJK
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BU of 7kjk by Molmil
The Neck region of Phage XM1 (6-fold symmetry)
分子名称: Collar spike protein, Head completion protein, Tail sheath protein, ...
著者Wang, Z, Klose, T, Jiang, W, Kuhn, R.J.
登録日2020-10-26
公開日2021-11-03
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
7KMX
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The capsid of Myoviridae Phage XM1
分子名称: Major capsid protein, Minor capsid protein
著者Wang, Z, Klose, T, Jiang, W, Kuhn, R.J.
登録日2020-11-03
公開日2021-11-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of Vibrio phage XM1, a simple contractile DNA injection machine
Biorxiv, 2021
3O34
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Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide
分子名称: BIOTIN, Histone H3.1, Transcription intermediary factor 1-alpha, ...
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
4QPL
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Crystal structure of RNF146(RING-WWE)/UbcH5a/iso-ADPr complex
分子名称: 2'-O-(5-O-phosphono-alpha-D-ribofuranosyl)adenosine 5'-(dihydrogen phosphate), E3 ubiquitin-protein ligase RNF146, Ubiquitin-conjugating enzyme E2 D1, ...
著者Wang, Z, DaRosa, P.A, Klevit, R.E, Xu, W.
登録日2014-06-23
公開日2014-10-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.
Nature, 517, 2015
4FC2
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Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain
分子名称: Poly(ADP-ribose) glycohydrolase, SULFATE ION
著者Wang, Z, Cheng, Z, Xu, W.
登録日2012-05-23
公開日2012-06-06
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase.
PLoS ONE, 9, 2014
7NEP
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Homology model of the in situ actomyosin complex from the A-band of mouse psoas muscle sarcomere in the rigor state
分子名称: Actin, alpha skeletal muscle, Myosin light chain 1/3, ...
著者Wang, Z, Grange, M, Wagner, T, Kho, A.L, Gautel, M, Raunser, S.
登録日2021-02-04
公開日2021-04-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (10.2 Å)
主引用文献The molecular basis for sarcomere organization in vertebrate skeletal muscle.
Cell, 184, 2021
3PDJ
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BU of 3pdj by Molmil
Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor
分子名称: Corticosteroid 11-beta-dehydrogenase isozyme 1, N-[trans-4-(3-amino-3-oxopropyl)-4-phenylcyclohexyl]-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wang, Z, Sudom, A, Walker, N.P.
登録日2010-10-22
公開日2011-10-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Synthesis and Optimization of Novel 4,4-Disubstituted Cyclohexylbenzamide Derivatives as Potent 11beta-HSD1 Inhibitors
Bioorg.Med.Chem.Lett., 21, 2011
3OQ1
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Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor
分子名称: 3-(2-fluoroethyl)-4-({4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]phenyl}sulfonyl)benzonitrile, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wang, Z, Sudom, A, Walker, N.P.
登録日2010-09-02
公開日2011-07-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors
Bioorg.Med.Chem.Lett., 20, 2010
8PA0
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BU of 8pa0 by Molmil
cvHsp (HspB7) C131S alpha-crystallin domain - filamin C (FLNC) domain 24 complex
分子名称: Filamin-C, Heat shock protein beta-7
著者Wang, Z, Benesch, J.L.P, Allison, T.M, Song, H, McDonough, M.A, Brem, J, Rabe, P.
登録日2023-06-06
公開日2024-10-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献cvHsp (HspB7) C131S alpha-crystallin domain - filamin C (FLNC) domain 24 complex
To Be Published
5HKP
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BU of 5hkp by Molmil
Crystal structure of mouse Tankyrase/human TRF1 complex
分子名称: Tankyrase-1, Telomeric repeat-binding factor 1
著者Wang, Z, Li, B, Rao, Z, Xu, W.
登録日2016-01-14
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
4L9K
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X-ray study of human serum albumin complexed with camptothecin
分子名称: (2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]butanoic acid, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-18
公開日2013-07-24
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
3O33
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Crystal structure of TRIM24 PHD-Bromo in the free state
分子名称: Transcription intermediary factor 1-alpha, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
4LB2
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X-ray study of human serum albumin complexed with idarubicin
分子名称: IDARUBICIN, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-20
公開日2013-07-24
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
4LB9
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X-ray study of human serum albumin complexed with etoposide
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, MYRISTIC ACID, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-20
公開日2013-07-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
3O37
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Crystal structure of TRIM24 PHD-Bromo complexed with H3(1-10)K4 peptide
分子名称: Histone H3.1, Transcription intermediary factor 1-alpha, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
4L9Q
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X-ray study of human serum albumin complexed with teniposide
分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-18
公開日2013-07-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
4L8U
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X-ray study of human serum albumin complexed with 9 amino camptothecin
分子名称: (2S)-2-[1-amino-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid, MYRISTIC ACID, Serum albumin
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-17
公開日2013-07-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
4LA0
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X-ray study of human serum albumin complexed with bicalutamide
分子名称: R-BICALUTAMIDE, SERUM ALBUMIN
著者Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C.
登録日2013-06-18
公開日2013-07-24
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830, 2013
5CP3
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Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides in Complex with Sulfathiazole
分子名称: 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, CALCIUM ION, GLYCEROL, ...
著者Wang, Z, Shen, J, Li, C, Li, Y, Wen, K, Yu, X, Zhang, X.
登録日2015-07-21
公開日2015-08-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
Anal. Chem., 91, 2019
3J7M
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BU of 3j7m by Molmil
Virus model of brome mosaic virus (first half data set)
分子名称: Capsid protein
著者Wang, Z, Hryc, C, Bammes, B, Afonine, P.V, Jakana, J, Chen, D.H, Liu, X, Baker, M.L, Kao, C, Ludtke, S.J, Schmid, M.F, Adams, P.D, Chiu, W.
登録日2014-07-18
公開日2014-09-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An atomic model of brome mosaic virus using direct electron detection and real-space optimization.
Nat Commun, 5, 2014

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