3O37

Crystal structure of TRIM24 PHD-Bromo complexed with H3(1-10)K4 peptide

Summary for 3O37

• Entry DOI: 10.2210/pdb3o37/pdb
• Related: 3O33 3O34 3O35 3O36
• Descriptor: Transcription intermediary factor 1-alpha, Histone H3.1, ZINC ION, ... (4 entities in total)
• Functional Keywords: trim24, phd finger, bromodomain, unmodified h3k4, breast cancer, transcription, transcription-protein binding complex, transcription/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: O15164 P68431
• Total number of polymer chains: 8
• Total formula weight: 90398.18

Authors

Wang, Z.,Patel, D.J. (deposition date: 2010-07-23, release date: 2010-12-15, Last modification date: 2024-02-21)

• Primary citation: Tsai, W.W.,Wang, Z.,Yiu, T.T.,Akdemir, K.C.,Xia, W.,Winter, S.,Tsai, C.Y.,Shi, X.,Schwarzer, D.,Plunkett, W.,Aronow, B.,Gozani, O.,Fischle, W.,Hung, M.C.,Patel, D.J.,Barton, M.C.; TRIM24 links a non-canonical histone signature to breast cancer.; Nature, 468:927-932, 2010; PubMed: 21164480; DOI: 10.1038/nature09542

Experimental method

X-RAY DIFFRACTION (2 Å)