4LB2

X-ray study of human serum albumin complexed with idarubicin

Summary for 4LB2

Related4L8U 4L9K 4L9Q 4LA0 4LB9
DescriptorSERUM ALBUMIN, IDARUBICIN (3 entities in total)
Functional Keywordsplasma protein, cancer, oncology drug complex, transport protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted P02768
Total number of polymer chains2
Total molecular weight135132.41
Authors
Wang, Z.,Ho, J.X.,Ruble, J.,Rose, J.P.,Carter, D.C. (deposition date: 2013-06-20, release date: 2013-07-24, Last modification date: 2014-02-19)
Primary citation
Wang, Z.M.,Ho, J.X.,Ruble, J.R.,Rose, J.,Ruker, F.,Ellenburg, M.,Murphy, R.,Click, J.,Soistman, E.,Wilkerson, L.,Carter, D.C.
Structural studies of several clinically important oncology drugs in complex with human serum albumin.
Biochim.Biophys.Acta, 1830:5356-5374, 2013
PubMed: 23838380 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbagen.2013.06.032
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24361.0%3.7%1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution