Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1203 件
6ILH
DownloadVisualize
BU of 6ilh by Molmil
Crystal Structure of human lysyl-tRNA synthetase L350H mutant
分子名称: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine-tRNA ligase
著者Hei, Z, Liu, Z, Wang, J, Fang, P.
登録日2018-10-18
公開日2019-02-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Retractile lysyl-tRNA synthetase-AIMP2 assembly in the human multi-aminoacyl-tRNA synthetase complex.
J. Biol. Chem., 294, 2019
3CMZ
DownloadVisualize
BU of 3cmz by Molmil
TEM-1 Class-A beta-lactamase L201P mutant apo structure
分子名称: Beta-lactamase TEM, PHOSPHATE ION
著者Marciano, D.C, Wang, X, Wang, J, Chen, Y, Thomas, V.L, Shoichet, B.K, Palzkill, T.
登録日2008-03-24
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Genetic and structural characterization of an L201P global suppressor substitution in TEM-1 beta-lactamase
J.Mol.Biol., 384, 2008
8DD9
DownloadVisualize
BU of 8dd9 by Molmil
Crystal Structure of SARS-CoV-2 Main Protease (Mpro) S144L Mutant in Complex with Inhibitor GC376
分子名称: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5
著者Lewandowski, E.M, Jacobs, L.M.C, Hu, Y, Tan, H, Wang, J, Chen, Y.
登録日2022-06-17
公開日2022-07-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir.
Acs Cent.Sci., 9, 2023
5H64
DownloadVisualize
BU of 5h64 by Molmil
Cryo-EM structure of mTORC1
分子名称: Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
著者Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H.
登録日2016-11-10
公開日2017-01-25
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
3R45
DownloadVisualize
BU of 3r45 by Molmil
Structure of a CENP-A-Histone H4 Heterodimer in complex with chaperone HJURP
分子名称: GLYCEROL, Histone H3-like centromeric protein A, Histone H4, ...
著者Hu, H, Liu, Y, Wang, M, Fang, J, Huang, H, Yang, N, Li, Y, Wang, J, Yao, X, Shi, Y, Li, G, Xu, R.M.
登録日2011-03-17
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP
Genes Dev., 25, 2011
8IBX
DownloadVisualize
BU of 8ibx by Molmil
Structure of R2 with 3'UTR and DNA in unwinding state
分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ...
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBW
DownloadVisualize
BU of 8ibw by Molmil
Structure of R2 with 3'UTR and DNA in binding state
分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ...
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBZ
DownloadVisualize
BU of 8ibz by Molmil
Structure of R2 with 5'ORF and 3'UTR
分子名称: 5ORF-linker-3UTR, Reverse transcriptase-like protein, ZINC ION
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
8IBY
DownloadVisualize
BU of 8iby by Molmil
Structure of R2 with 5'ORF
分子名称: 5'ORF RNA, Reverse transcriptase-like protein, ZINC ION
著者Deng, P, Tan, S, Wang, J, Liu, J.J.
登録日2023-02-10
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon.
Cell, 186, 2023
1QRZ
DownloadVisualize
BU of 1qrz by Molmil
CATALYTIC DOMAIN OF PLASMINOGEN
分子名称: PLASMINOGEN
著者Peisach, E, Wang, J, de los Santos, T, Reich, E, Ringe, D.
登録日1999-06-16
公開日1999-10-14
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the proenzyme domain of plasminogen.
Biochemistry, 38, 1999
7U15
DownloadVisualize
BU of 7u15 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U16
DownloadVisualize
BU of 7u16 by Molmil
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U17
DownloadVisualize
BU of 7u17 by Molmil
TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U10
DownloadVisualize
BU of 7u10 by Molmil
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U11
DownloadVisualize
BU of 7u11 by Molmil
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U13
DownloadVisualize
BU of 7u13 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U12
DownloadVisualize
BU of 7u12 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U18
DownloadVisualize
BU of 7u18 by Molmil
TMEM106B(120-254) T185S protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, TMEM106B protein
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-20
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U0Z
DownloadVisualize
BU of 7u0z by Molmil
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
分子名称: Isoform Tau-E of Microtubule-associated protein tau
著者FItzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
7U14
DownloadVisualize
BU of 7u14 by Molmil
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
著者Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A.
登録日2022-02-19
公開日2022-03-23
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
5GQH
DownloadVisualize
BU of 5gqh by Molmil
Cryo-EM structure of PaeCas3-AcrF3 complex
分子名称: CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3
著者Zhang, X, Ma, J, Wang, Y, Wang, J.
登録日2016-08-07
公開日2016-09-21
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
5X83
DownloadVisualize
BU of 5x83 by Molmil
Structure of DCC FN456 domains
分子名称: Netrin receptor DCC
著者Finci, F.I, Xiao, J, Wang, J.
登録日2017-02-28
公開日2017-09-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC
Protein Cell, 8, 2017
4Z0B
DownloadVisualize
BU of 4z0b by Molmil
Crystal Structure of the Fab Fragment of Anti-ofloxacin Antibody and Exploration Its Receptor Binding Site
分子名称: PHOSPHATE ION, antibody heavy chain, antibody light chain
著者He, K, Du, X, Sheng, W, Zhou, X, Wang, J, Wang, S.
登録日2015-03-26
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of the Fab Fragment of an Anti-ofloxacin Antibody and Exploration of Its Specific Binding.
J.Agric.Food Chem., 64, 2016
2O9Q
DownloadVisualize
BU of 2o9q by Molmil
The crystal structure of Bovine Trypsin complexed with a small inhibition peptide ORB2K
分子名称: CALCIUM ION, Cationic trypsin, ORB2K, ...
著者Li, J, Zhang, C, Xu, X, Wang, J, Gong, W, Lai, R.
登録日2006-12-14
公開日2007-12-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献From protease inhibitor to antibiotics: single point mutation makes tremendous functional shift
To be Published
2BM2
DownloadVisualize
BU of 2bm2 by Molmil
human beta-II tryptase in complex with 4-(3-Aminomethyl-phenyl)- piperidin-1-yl-(5-phenethyl- pyridin-3-yl)-methanone
分子名称: 1-[3-(1-{[5-(2-PHENYLETHYL)PYRIDIN-3-YL]CARBONYL}PIPERIDIN-4-YL)PHENYL]METHANAMINE, HUMAN BETA2 TRYPTASE
著者Maignan, S, Guilloteau, J.-P, Dupuy, A, Levell, J, Astles, P, Eastwood, P, Cairns, J, Houille, O, Aldous, S, Merriman, G, Whiteley, B, Pribish, J, Czekaj, M, Liang, G, Davidson, J, Harrison, T, Morley, A, Watson, S, Fenton, G, Mccarthy, C, Romano, J, Mathew, R, Engers, D, Gardyan, M, Sides, K, Kwong, J, Tsay, J, Rebello, S, Shen, L, Wang, J, Luo, Y, Giardino, O, Lim, H.-K, Smith, K, Pauls, H.
登録日2005-03-09
公開日2005-03-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure Based Design of 4-(3-Aminomethylphenyl) Piperidinyl-1-Amides: Novel, Potent, Selective, and Orally Bioavailable Inhibitors of Bii Tryptase
Bioorg.Med.Chem., 13, 2005

224931

件を2024-09-11に公開中

PDB statisticsPDBj update infoContact PDBjnumon