Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1204 件
2V5Z
DownloadVisualize
BU of 2v5z by Molmil
Structure of human MAO B in complex with the selective inhibitor safinamide
分子名称: (S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE], Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE
著者Binda, C, Wang, J, Pisani, L, Caccia, C, Carotti, A, Salvati, P, Edmondson, D.E, Mattevi, A.
登録日2007-07-12
公開日2007-10-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.
J.Med.Chem., 50, 2007
2V60
DownloadVisualize
BU of 2v60 by Molmil
Structure of human MAO B in complex with the selective inhibitor 7-(3- chlorobenzyloxy)-4-carboxaldehyde-coumarin
分子名称: 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE, AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE
著者Binda, C, Wang, J, Pisani, L, Caccia, C, Carotti, A, Salvati, P, Edmondson, D.E, Mattevi, A.
登録日2007-07-12
公開日2007-10-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs.
J.Med.Chem., 50, 2007
5IRI
DownloadVisualize
BU of 5iri by Molmil
Structure of the mouse SAD-B AIS-KA1 fragment
分子名称: Serine/threonine-protein kinase BRSK1
著者Ma, H, Wu, J.X, Wang, J, Wu, J.W.
登録日2016-03-13
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and inhibition analysis of the mouse SAD-B C-terminal fragment
Biosci.Biotechnol.Biochem., 2016
7TQL
DownloadVisualize
BU of 7tql by Molmil
CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D.
登録日2022-01-26
公開日2022-04-27
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
2V61
DownloadVisualize
BU of 2v61 by Molmil
Structure of human MAO B in complex with the selective inhibitor 7-(3- chlorobenzyloxy)-4-(methylamino)methyl-coumarin
分子名称: 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE, AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE
著者Binda, C, Wang, J, Pisani, L, Caccia, C, Carotti, A, Salvati, P, Edmondson, D.E, Mattevi, A.
登録日2007-07-13
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of Human Monoamine Oxidase B Complexes with Selective Noncovalent Inhibitors: Safinamide and Coumarin Analogs.
J.Med.Chem., 50, 2007
1OZE
DownloadVisualize
BU of 1oze by Molmil
Crystal Structures of the Ferric, Ferrous, and Ferrous-NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1:Catalytic Implications
分子名称: Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE
著者Lad, L, Wang, J, Li, H, Friedman, J, Ortiz de Montellano, P.R, Poulos, T.L.
登録日2003-04-08
公開日2003-08-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal structures of the ferric, ferrous, and ferrous-NO forms of the Asp140Ala mutant of human heme oxygenase-1: catalytic implications
J.Mol.Biol., 330, 2003
1M4A
DownloadVisualize
BU of 1m4a by Molmil
Crystal Structure of Human Interleukin-2 Y31C Covalently Modified at C31 with (1H-Indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid
分子名称: (1H-INDOL-3-YL)-(2-MERCAPTO-ETHOXYIMINO)-ACETIC ACID, GLYCEROL, interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
1M48
DownloadVisualize
BU of 1m48 by Molmil
Crystal Structure of Human IL-2 Complexed with (R)-N-[2-[1-(Aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-L-phenylalanine methyl ester
分子名称: 2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3-(4-PHENYLETHYNYL-PHENYL)-PROPIONIC ACID METHYL ESTER, interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
1M47
DownloadVisualize
BU of 1m47 by Molmil
Crystal Structure of Human Interleukin-2
分子名称: SULFATE ION, interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, Wells, J.A, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface.
Proc.Natl.Acad.Sci.USA, 100, 2003
1M4C
DownloadVisualize
BU of 1m4c by Molmil
Crystal Structure of Human Interleukin-2
分子名称: interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
1M49
DownloadVisualize
BU of 1m49 by Molmil
Crystal Structure of Human Interleukin-2 Complexed with SP-1985
分子名称: 2-[2-(1-CARBAMIMIDOYL-PIPERIDIN-3-YL)-ACETYLAMINO]-3-{4-[2-(3-OXALYL-1H-INDOL-7-YL)ETHYL]-PHENYL}-PROPIONIC ACID METHYL ESTER, interleukin-2
著者Arkin, M.A, Randal, M, DeLano, W.L, Hyde, J, Luong, T.N, Oslob, J.D, Raphael, D.R, Taylor, L, Wang, J, McDowell, R.S, Wells, J.A, Braisted, A.C.
登録日2002-07-02
公開日2002-07-31
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of small molecules to an adaptive protein-protein interface
Proc.Natl.Acad.Sci.USA, 100, 2003
6ULW
DownloadVisualize
BU of 6ulw by Molmil
Adenylation, ketoreductase, and pseudo Asub multidomain structure of a keto acid-selecting NRPS module
分子名称: Amino acid adenylation domain-containing protein, CALCIUM ION, MAGNESIUM ION
著者Alonzo, D.A, Wang, J, Chiche-Lapierre, C, Schmeing, T.M.
登録日2019-10-08
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis.
Nat.Chem.Biol., 16, 2020
6UIB
DownloadVisualize
BU of 6uib by Molmil
Crystal structure of IL23 bound to peptide 23-652
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ...
著者Durbin, J.D, Wang, J, Afshar, S.
登録日2019-09-30
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage.
Plos One, 15, 2020
4YR8
DownloadVisualize
BU of 4yr8 by Molmil
Crystal structure of JNK in complex with a regulator protein
分子名称: CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8
著者Liu, X, Wang, J, Wu, J.W, Wang, Z.X.
登録日2015-03-14
公開日2016-03-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.
Nat Commun, 7, 2016
8H2H
DownloadVisualize
BU of 8h2h by Molmil
Cryo-EM structure of a Group II Intron Complexed with its Reverse Transcriptase
分子名称: Group II intron-encoded protein LtrA, LtrB, RNA (5'-R(P*CP*AP*CP*AP*UP*CP*CP*AP*UP*AP*AP*C)-3')
著者Liu, N, Dong, X.L, Qu, G.S, Wang, J, Wang, H.W, Belfort, M.
登録日2022-10-06
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Functionalized graphene grids with various charges for single-particle cryo-EM.
Nat Commun, 13, 2022
8HF0
DownloadVisualize
BU of 8hf0 by Molmil
DmDcr-2/R2D2/LoqsPD with 50bp-dsRNA in Dimer state
分子名称: Dicer-2, isoform A, LD06392p, ...
著者Su, S, Wang, J, Wang, H.W, Ma, J.
登録日2022-11-09
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural mechanism of R2D2 and Loqs-PD synergistic modulation on DmDcr-2 oligomers.
Nat Commun, 14, 2023
8WGF
DownloadVisualize
BU of 8wgf by Molmil
The Crystal Structure of JNK3 from Biortus.
分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 10, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J.
登録日2023-09-21
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Crystal Structure of JNK3 from Biortus.
To Be Published
8PYI
DownloadVisualize
BU of 8pyi by Molmil
Human IGF1R with inhibitor 6
分子名称: 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol, Insulin-like growth factor 1 receptor beta chain
著者Dreyer, M.K, Wang, J, Elkins, J.M.
登録日2023-07-25
公開日2023-09-20
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Human IGF1R with inhibitor 6
To Be Published
8PYJ
DownloadVisualize
BU of 8pyj by Molmil
Human IGF1R with inhibitor 8
分子名称: 5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ...
著者Dreyer, M.K, Wang, J, Elkins, J.M.
登録日2023-07-25
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Human IGF1R with inhibitor 8
To Be Published
8PYK
DownloadVisualize
BU of 8pyk by Molmil
Human IGF1R with inhibitor 47
分子名称: 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, Insulin-like growth factor 1 receptor beta chain, NICKEL (II) ION
著者Dreyer, M.K, Wang, J, Elkins, J.M.
登録日2023-07-25
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Human IGF1R with inhibitor 47
To Be Published
8PYL
DownloadVisualize
BU of 8pyl by Molmil
Human IGF1R with inhibitor 53
分子名称: (5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ...
著者Dreyer, M.K, Wang, J, Elkins, J.M.
登録日2023-07-25
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Human IGF1R with inhibitor 53
To Be Published
8PYM
DownloadVisualize
BU of 8pym by Molmil
Human IGF1R with inhibitor 54
分子名称: 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ...
著者Dreyer, M.K, Wang, J, Elkins, J.M.
登録日2023-07-25
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Human IGF1R with inhibitor 54
To Be Published
8PYN
DownloadVisualize
BU of 8pyn by Molmil
Human IGF1R with inhibitor 56
分子名称: 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfonyl)phenyl]imidazolidine-2,4-dione, CADMIUM ION, Insulin-like growth factor 1 receptor beta chain, ...
著者Dreyer, M.K, Wang, J, Elkins, J.M.
登録日2023-07-25
公開日2023-09-20
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Human IGF1R with inhibitor 56
To Be Published
6WAY
DownloadVisualize
BU of 6way by Molmil
C-terminal SH2 domain of p120RasGAP in complex with p190RhoGAP phosphotyrosine peptide
分子名称: Ras GTPase-activating protein 1, Rho GTPase-activating protein 35
著者Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J.
登録日2020-03-26
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
J.Biol.Chem., 295, 2020
6C6C
DownloadVisualize
BU of 6c6c by Molmil
Structure of glycolipid aGSA[20,6P] in complex with mouse CD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ...
著者Zajonc, D.M, Wang, J.
登録日2018-01-18
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon