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8PYI

Human IGF1R with inhibitor 6

This is a non-PDB format compatible entry.
Summary for 8PYI
Entry DOI10.2210/pdb8pyi/pdb
DescriptorInsulin-like growth factor 1 receptor beta chain, 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol (3 entities in total)
Functional Keywordstyrosine, kinase, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains8
Total formula weight297596.20
Authors
Dreyer, M.K.,Wang, J.,Elkins, J.M. (deposition date: 2023-07-25, release date: 2023-09-20)
Primary citationDreyer, M.K.,Wang, J.,Elkins, J.M.
Human IGF1R with inhibitor 6
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.06 Å)
Structure validation

218853

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