6ULW
Adenylation, ketoreductase, and pseudo Asub multidomain structure of a keto acid-selecting NRPS module
Summary for 6ULW
Entry DOI | 10.2210/pdb6ulw/pdb |
Descriptor | Amino acid adenylation domain-containing protein, CALCIUM ION, MAGNESIUM ION (3 entities in total) |
Functional Keywords | nrps, nonribosomal peptide synthetase, non-ribosomal peptide synthetase, adenylation, adenylation domain, depsipeptide, cereulide, valinomycin, natural product, adenylate, keto acid, ketoacid, ketoreductase, short chain dehydrogenase, biosynthetic protein |
Biological source | Bacillus stratosphericus LAMA 585 |
Total number of polymer chains | 4 |
Total formula weight | 596067.12 |
Authors | Alonzo, D.A.,Wang, J.,Chiche-Lapierre, C.,Schmeing, T.M. (deposition date: 2019-10-08, release date: 2020-02-19, Last modification date: 2023-10-11) |
Primary citation | Alonzo, D.A.,Chiche-Lapierre, C.,Tarry, M.J.,Wang, J.,Schmeing, T.M. Structural basis of keto acid utilization in nonribosomal depsipeptide synthesis. Nat.Chem.Biol., 16:493-496, 2020 Cited by PubMed: 32066969DOI: 10.1038/s41589-020-0481-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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