1M47

Crystal Structure of Human Interleukin-2

Summary for 1M47

Entry DOI	10.2210/pdb1m47/pdb
Related	1M48 1M49 1M4A 1M4B 1M4C
Descriptor	interleukin-2, SULFATE ION (3 entities in total)
Functional Keywords	cytokine, four-helix bundle
Biological source	Homo sapiens (human)
Cellular location	Secreted: P60568
Total number of polymer chains	1
Total formula weight	15628.10
Authors	Arkin, M.A.,Randal, M.,DeLano, W.L.,Hyde, J.,Luong, T.N.,Oslob, J.D.,Raphael, D.R.,Taylor, L.,Wang, J.,Wells, J.A.,McDowell, R.S.,Wells, J.A.,Braisted, A.C. (deposition date: 2002-07-02, release date: 2002-07-31, Last modification date: 2017-10-11)
Primary citation	Arkin, M.R.,Randal, M.,DeLano, W.L.,Hyde, J.,Luong, T.N.,Oslob, J.D.,Raphael, D.R.,Taylor, L.,Wang, J.,McDowell, R.S.,Wells, J.A.,Braisted, A.C. Binding of small molecules to an adaptive protein-protein interface. Proc.Natl.Acad.Sci.USA, 100:1603-1608, 2003 Cited by PubMed: 12582206 DOI: 10.1073/pnas.252756299 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation