5ZM5
 
 | | Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution | | Descriptor: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | Authors: | Dong, J, Wang, J, Wu, J.W. | | Deposit date: | 2018-04-01 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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5EFI
 | | Crystal structure of mouse CD1d in complex with the p99p lipopeptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | Authors: | Girardi, E, Wang, J, Zajonc, D.M. | | Deposit date: | 2015-10-23 | | Release date: | 2016-03-30 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of an alpha-Helical Peptide and Lipopeptide Bound to the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule CD1d.
J.Biol.Chem., 291, 2016
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6C6F
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5ZM6
 | | Crystal structure of ORP1-ORD in complex with PI(4,5)P2 | | Descriptor: | ACETATE ION, Oxysterol-binding protein-related protein 1, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | | Authors: | Dong, J, Wang, J, Luo, Z, Wu, J.W. | | Deposit date: | 2018-04-01 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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6E59
 | | Crystal structure of the human NK1 tachykinin receptor | | Descriptor: | 1-(4-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1H-1,2,3-triazol-5-yl)-N,N-dimethylmethanamine, Substance-P receptor, GlgA glycogen synthase, ... | | Authors: | Yin, J, Clark, L, Chapman, K, Shao, Z, Borek, D, Xu, Q, Wang, J, Rosenbaum, D.M. | | Deposit date: | 2018-07-19 | | Release date: | 2018-12-12 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Crystal structure of the human NK1tachykinin receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BVN
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6LSA
 | | Complex structure of bovine herpesvirus 1 glycoprotein D and bovine nectin-1 IgV | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ... | | Authors: | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | | Deposit date: | 2020-01-17 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.204 Å) | | Cite: | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor.
Sci Adv, 6, 2020
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5ZM7
 | | Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | | Descriptor: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | | Authors: | Dong, J, Wang, J, Wu, J.W. | | Deposit date: | 2018-04-01 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.401 Å) | | Cite: | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun, 10, 2019
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6LS9
 | | Crystal structure of bovine herpesvirus 1 glycoprotein D | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D | | Authors: | Yue, D, Chen, Z.J, Yang, F.L, Ye, F, Lin, S, Cheng, Y.W, Wang, J.C, Chen, Z.M, Lin, X, Yang, J, Chen, H, Zhang, Z.L, You, Y, Sun, H.L, Wen, A, Wang, L.L, Zheng, Y, Cao, Y, Li, Y.H, Lu, G.W. | | Deposit date: | 2020-01-17 | | Release date: | 2020-06-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Crystal structure of bovine herpesvirus 1 glycoprotein D bound to nectin-1 reveals the basis for its low-affinity binding to the receptor.
Sci Adv, 6, 2020
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4EDG
 | | The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ... | | Authors: | Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M. | | Deposit date: | 2012-03-27 | | Release date: | 2012-07-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.003 Å) | | Cite: | Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
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6EDJ
 | | Cryo-EM structure of Woodchuck hepatitis virus capsid | | Descriptor: | External core antigen | | Authors: | Zhao, Z, Wang, J.C, Zlotnick, A. | | Deposit date: | 2018-08-09 | | Release date: | 2019-05-01 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.52 Å) | | Cite: | Structural Differences between the Woodchuck Hepatitis Virus Core Protein in the Dimer and Capsid States Are Consistent with Entropic and Conformational Regulation of Assembly.
J.Virol., 93, 2019
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7DAC
 | | Human RIPK3 amyloid fibril revealed by solid-state NMR | | Descriptor: | Receptor-interacting serine/threonine-protein kinase 3 | | Authors: | Wu, X.L, Zhang, J, Dong, X.Q, Liu, J, Li, B, Hu, H, Wang, J, Wang, H.Y, Lu, J.X. | | Deposit date: | 2020-10-16 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-01 | | Method: | SOLID-STATE NMR | | Cite: | The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4FC7
 | | Studies on DCR shed new light on peroxisomal beta-oxidation: Crystal structure of the ternary complex of pDCR | | Descriptor: | COENZYME A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Peroxisomal 2,4-dienoyl-CoA reductase | | Authors: | Hua, T, Wu, D, Wang, J, Shaw, N, Liu, Z.-J. | | Deposit date: | 2012-05-24 | | Release date: | 2012-07-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids
J.Biol.Chem., 287, 2012
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4FC6
 | | Studies on DCR shed new light on peroxisomal beta-oxidation: Crystal structure of the ternary complex of pDCR | | Descriptor: | HEXANOYL-COENZYME A, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Peroxisomal 2,4-dienoyl-CoA reductase | | Authors: | Hua, T, Wu, D, Wang, J, Shaw, N, Liu, Z.-J. | | Deposit date: | 2012-05-24 | | Release date: | 2012-07-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal beta-oxidation of unsaturated fatty acids
J.Biol.Chem., 287, 2012
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4O33
 | | Crystal Structure of human PGK1 3PG and terazosin(TZN) ternary complex | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone | | Authors: | Li, X.L, Finci, L.I, Wang, J.H. | | Deposit date: | 2013-12-18 | | Release date: | 2014-10-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
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4O3F
 | | Crystal Structure of mouse PGK1 3PG and terazosin(TZN) ternary complex | | Descriptor: | 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase 1, [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl][(2R)-tetrahydrofuran-2-yl]methanone | | Authors: | Li, X.L, Finci, I.L, Wang, J.H. | | Deposit date: | 2013-12-18 | | Release date: | 2014-10-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.106 Å) | | Cite: | Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat.Chem.Biol., 11, 2015
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4M9X
 | | Crystal structure of CED-4 bound CED-3 fragment | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | | Authors: | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | | Deposit date: | 2013-08-15 | | Release date: | 2013-10-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.344 Å) | | Cite: | Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
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5XOU
 | | Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 7T8 on the guide strand | | Descriptor: | DNA (5'-D(*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*TP*GP*GP*TP*TP*GP*T)-3'), MAGNESIUM ION, ... | | Authors: | Sheng, G, Wang, J, Zhao, H, Wang, Y. | | Deposit date: | 2017-05-31 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes
Nucleic Acids Res., 45, 2017
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5XPG
 | | Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 6'U7' on the target strand | | Descriptor: | 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*A P*GP*T)-3', 5'-R(*UP*AP*U*AP*CP*AP*AP*CP*CP*UP*AP*CP*AP*UP*AP*CP*CP*UP*CP* G)-3', MAGNESIUM ION, ... | | Authors: | Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, J.D, Wang, Y. | | Deposit date: | 2017-06-02 | | Release date: | 2018-04-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes.
Nucleic Acids Res., 45, 2017
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4Y6K
 | | Complex structure of presenilin homologue PSH bound to an inhibitor | | Descriptor: | N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide, Uncharacterized protein PSH | | Authors: | Dang, S, Wu, S, Wang, J, Shi, Y. | | Deposit date: | 2015-02-13 | | Release date: | 2015-03-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.855 Å) | | Cite: | Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
Proc.Natl.Acad.Sci.USA, 112, 2015
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4M9Y
 | | Crystal structure of CED-4 bound CED-3 fragment | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | | Authors: | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | | Deposit date: | 2013-08-15 | | Release date: | 2013-10-23 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Mechanistic insights into CED-4-mediated activation of CED-3.
Genes Dev., 27, 2013
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3P22
 | | Crystal structure of the ENE, a viral RNA stability element, in complex with A9 RNA | | Descriptor: | Core ENE hairpin from KSHV PAN RNA, oligo(A)9 RNA | | Authors: | Mitton-Fry, R.M, DeGregorio, S.J, Wang, J, Steitz, T.A, Steitz, J.A. | | Deposit date: | 2010-10-01 | | Release date: | 2010-12-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Poly(A) tail recognition by a viral RNA element through assembly of a triple helix.
Science, 330, 2010
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5Y0I
 | | Solution structure of arenicin-3 derivative N1 | | Descriptor: | NZ17074(N1) | | Authors: | Liu, X.H, Wang, J.H. | | Deposit date: | 2017-07-17 | | Release date: | 2017-07-26 | | Method: | SOLUTION NMR | | Cite: | Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis
Sci Rep, 7, 2017
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8XCG
 | | Tail tip complex of bacteriophage lambda in the open state | | Descriptor: | IRON/SULFUR CLUSTER, Tail tip assembly protein I, Tail tip protein L, ... | | Authors: | Ge, X.F, Wang, J.W. | | Deposit date: | 2023-12-09 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Structural mechanism of bacteriophage lambda tail's interaction with the bacterial receptor.
Nat Commun, 15, 2024
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8XCI
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