4Y6K
Complex structure of presenilin homologue PSH bound to an inhibitor
Summary for 4Y6K
Entry DOI | 10.2210/pdb4y6k/pdb |
Related PRD ID | PRD_002147 |
Descriptor | Uncharacterized protein PSH, N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide (2 entities in total) |
Functional Keywords | complex, inhibitor, membrane protein-inhibitor complex, membrane protein/inhibitor |
Biological source | Methanoculleus marisnigri JR1 |
Total number of polymer chains | 4 |
Total formula weight | 128862.75 |
Authors | |
Primary citation | Dang, S.,Wu, S.,Wang, J.,Li, H.,Huang, M.,He, W.,Li, Y.M.,Wong, C.C.,Shi, Y. Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH Proc.Natl.Acad.Sci.USA, 112:3344-3349, 2015 Cited by PubMed: 25733893DOI: 10.1073/pnas.1502150112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.855 Å) |
Structure validation
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