Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1554 件
6JD7
DownloadVisualize
BU of 6jd7 by Molmil
Crystal structure of anti-CRISPR protein AcrIIC2 dimer
分子名称: ACETATE ION, AcrIIC2, MAGNESIUM ION
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.L.
登録日2019-01-31
公開日2019-05-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6JDV
DownloadVisualize
BU of 6jdv by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in catalytic state
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, MAGNESIUM ION, ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-02
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
2AOI
DownloadVisualize
BU of 2aoi by Molmil
Crystal structure analysis of HIV-1 protease with a substrate analog P1-P6
分子名称: PEPTIDE INHIBITOR, POL POLYPROTEIN, SULFATE ION
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2005-08-12
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
6JDQ
DownloadVisualize
BU of 6jdq by Molmil
Crystal structure of Nme1Cas9 in complex with sgRNA
分子名称: CRISPR-associated endonuclease Cas9, sgRNA
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-02
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
6JE3
DownloadVisualize
BU of 6je3 by Molmil
Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhang
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target DNA strand, ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-02-03
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.931 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
3GO7
DownloadVisualize
BU of 3go7 by Molmil
Crystal Structure of M. tuberculosis ribokinase (Rv2436) in complex with ribose
分子名称: MAGNESIUM ION, RIBOKINASE RBSK, alpha-D-ribofuranose
著者Masters, E.I, Sun, Y, Wang, Y, Parker, W.B, Li, R.
登録日2009-03-18
公開日2010-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)
To be Published
4N76
DownloadVisualize
BU of 4n76 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and cleaved target DNA with Mn2+
分子名称: 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', Argonaute, ...
著者Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
登録日2013-10-15
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N41
DownloadVisualize
BU of 4n41 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 15-mer target DNA
分子名称: 5'-D(*AP*AP*CP*CP*TP*AP*CP*TP*GP*CP*CP*TP*CP*G)-3', 5'-D(P*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*T*GP*TP*AP*TP*AP*GP*T)-3', ...
著者Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
登録日2013-10-08
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.248 Å)
主引用文献Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
7VMA
DownloadVisualize
BU of 7vma by Molmil
The X-ray crystallographic structure of amylo-alpha-1,6-glucosidase from Thermococcus gammatolerans STB12
分子名称: Amylo-alpha-1,6-glucosidase, putative archaeal type glycogen debranching enzyme (Gde)
著者Li, Z.F, Ban, X.F, Wang, Y.M, Li, C.M, Gu, Z.B.
登録日2021-10-08
公開日2022-10-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献The X-ray Crystallographic Structure of Amylo-alpha-1,6-glucosidase from Thermococcus gannatilerans STB12
To Be Published
6KC8
DownloadVisualize
BU of 6kc8 by Molmil
Crystal structure of WT Nme1Cas9 in complex with sgRNA and target DNA (ATATGATT PAM) in post-cleavage state
分子名称: CRISPR-associated endonuclease Cas9, DNA (5'-D(*AP*TP*AP*TP*GP*AP*TP*TP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*TP*CP*AP*TP*AP*TP*GP*TP*A)-3'), ...
著者Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
登録日2019-06-27
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
4JKR
DownloadVisualize
BU of 4jkr by Molmil
Crystal Structure of E. coli RNA Polymerase in complex with ppGpp
分子名称: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, Wang, Y, Steitz, T.A.
登録日2013-03-11
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex.
Mol.Cell, 50, 2013
7CZ5
DownloadVisualize
BU of 7cz5 by Molmil
Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex
分子名称: CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2020-09-07
公開日2020-11-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
5GQH
DownloadVisualize
BU of 5gqh by Molmil
Cryo-EM structure of PaeCas3-AcrF3 complex
分子名称: CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3
著者Zhang, X, Ma, J, Wang, Y, Wang, J.
登録日2016-08-07
公開日2016-09-21
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
7ESI
DownloadVisualize
BU of 7esi by Molmil
Crystal structure of the collagenase unit of a Vibrio collagenase from Vibrio harveyi VHJR7 at 1. 8 angstrom resolution.
分子名称: CALCIUM ION, Collagenase unit (CU), Peptide P1, ...
著者Cao, H.Y, Wang, Y, Peng, M, Zhang, Y.Z.
登録日2021-05-11
公開日2022-02-09
最終更新日2023-02-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Vibrio collagenase VhaC provides insight into the mechanism of bacterial collagenolysis.
Nat Commun, 13, 2022
3RJX
DownloadVisualize
BU of 3rjx by Molmil
Crystal Structure of Hyperthermophilic Endo-Beta-1,4-glucanase
分子名称: Endoglucanase FnCel5A
著者Zheng, B.S, Yang, W, Zhao, X.Y, Wang, Y.G, Lou, Z.Y, Rao, Z.H, Feng, Y.
登録日2011-04-15
公開日2011-12-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of hyperthermophilic endo-beta-1,4-glucanase: implications for catalytic mechanism and thermostability.
J.Biol.Chem., 287, 2012
7EVP
DownloadVisualize
BU of 7evp by Molmil
Cryo-EM structure of the Gp168-beta-clamp complex
分子名称: Beta sliding clamp, Sliding clamp inhibitor
著者Liu, B, Li, S, Liu, Y, Chen, H, Hu, Z, Wang, Z, Gou, L, Zhang, L, Ma, B, Wang, H, Matthews, S, Wang, Y, Zhang, K.
登録日2021-05-21
公開日2022-02-16
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Bacteriophage Twort protein Gp168 is a beta-clamp inhibitor by occupying the DNA sliding channel.
Nucleic Acids Res., 49, 2021
2AOH
DownloadVisualize
BU of 2aoh by Molmil
Crystal structure analysis of HIV-1 Protease mutant V82A with a substrate analog P6-PR
分子名称: CHLORIDE ION, PEPTIDE INHIBITOR, POL POLYPROTEIN, ...
著者Tie, Y, Boross, P.I, Wang, Y.F, Gaddis, L, Liu, F, Chen, X, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2005-08-12
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.
Febs J., 272, 2005
1K1T
DownloadVisualize
BU of 1k1t by Molmil
Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance
分子名称: N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN, SULFATE ION
著者Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2001-09-25
公開日2002-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Combining mutations in HIV-1 protease to understand mechanisms of resistance.
Proteins, 48, 2002
1K2C
DownloadVisualize
BU of 1k2c by Molmil
Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance
分子名称: N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, PROTEASE RETROPEPSIN
著者Mahalingam, B, Boross, P, Wang, Y.-F, Louis, J.M, Fischer, C, Tozser, J, W Harrison, R, Weber, I.T.
登録日2001-09-26
公開日2002-07-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Combining mutations in HIV-1 protease to understand mechanisms of resistance.
Proteins, 48, 2002
1A8F
DownloadVisualize
BU of 1a8f by Molmil
HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE
分子名称: CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN
著者Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N.
登録日1998-03-25
公開日1998-06-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
5DGU
DownloadVisualize
BU of 5dgu by Molmil
Crystal Structure of HIV-1 Protease Inhibitors Containing Substituted fused-Tetrahydropyranyl Tetrahydrofuran as P2-Ligand GRL-004-11A
分子名称: (3R,3aR,4S,7aS)-3-methoxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ...
著者Agniswamy, J, Wang, Y.-F, Weber, I.T.
登録日2015-08-28
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligands.
Org.Biomol.Chem., 13, 2015
4J1J
DownloadVisualize
BU of 4j1j by Molmil
Leanyer orthobunyavirus nucleoprotein-ssDNA complex
分子名称: DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3'), Nucleocapsid
著者Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
6JEA
DownloadVisualize
BU of 6jea by Molmil
crystal structure of a beta-N-acetylhexosaminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, ZINC ION
著者Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M.
登録日2019-02-04
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.275 Å)
主引用文献Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila.
Biochem. Biophys. Res. Commun., 511, 2019
5YEH
DownloadVisualize
BU of 5yeh by Molmil
Crystal structure of CTCF ZFs4-8-eCBS
分子名称: DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), Transcriptional repressor CTCF, ...
著者Yin, M, Wang, J, Wang, M, Li, X, Wang, Y.
登録日2017-09-17
公開日2017-11-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.328 Å)
主引用文献Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites
Cell Res., 27, 2017
4ZHW
DownloadVisualize
BU of 4zhw by Molmil
Crystal structure of a bacterial signalling protein (N-terminal truncation)
分子名称: YfiB
著者Li, S, Li, T, Wang, Y, Bartlam, M.
登録日2015-04-27
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon