4N41
Structure of Thermus thermophilus Argonaute bound to guide DNA and 15-mer target DNA
Summary for 4N41
| Entry DOI | 10.2210/pdb4n41/pdb |
| Related | 3DLH 3HM9 3HVR 4N47 4N76 4NCA 4NCB |
| Descriptor | Argonaute, 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*T*GP*TP*AP*TP*AP*GP*T)-3', 5'-D(P*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', ... (6 entities in total) |
| Functional Keywords | argonaute, rna interference, dna interference, nuclear protein-dna complex, nuclear protein/dna |
| Biological source | Thermus thermophilus |
| Total number of polymer chains | 6 |
| Total formula weight | 174763.20 |
| Authors | |
| Primary citation | Sheng, G.,Zhao, H.,Wang, J.,Rao, Y.,Tian, W.,Swarts, D.C.,van der Oost, J.,Patel, D.J.,Wang, Y. Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage. Proc.Natl.Acad.Sci.USA, 111:652-657, 2014 Cited by PubMed: 24374628DOI: 10.1073/pnas.1321032111 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.248 Å) |
Structure validation
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