4N41

Structure of Thermus thermophilus Argonaute bound to guide DNA and 15-mer target DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Argonaute	polymer	685	76728.7	2	UniProt (Q746M7) Pfam (PF22472) Pfam (PF18309) Pfam (PF22474)	Thermus thermophilus
2	C, D (C, E)	5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*T*GP*TP*AP*TP*AP*GP*T)-3'	polymer	21	6588.3	2
3	E (D)	5'-D(P*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'	polymer	13	3871.5	1
4	F (F)	5'-D(*AP*AP*CP*CP*TP*AP*CP*TP*GP*CP*CP*TP*CP*G)-3'	polymer	14	4184.7	1
5	G, H, I (B, C, E)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
6	J, K, L, M, N... (A, B, C, E, D...)	water	water		18.0	170	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	174690.3
Non-Polymers*	Number of molecules	3
	Total formula weight	72.9
All*	Total formula weight	174763.2

*Water molecules are not included.