7UY7
 
 | | Tetrahymena CST with Polymerase alpha-Primase | | 分子名称: | DNA polymerase, Telomerase associated protein p50, Telomerase-associated protein of 19 kDa, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY5
 | | Tetrahymena telomerase with CST | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY6
 | | Tetrahymena telomerase at 2.9 Angstrom resolution | | 分子名称: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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7UY8
 | | Tetrahymena Polymerase alpha-Primase | | 分子名称: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | | 著者 | He, Y, Song, H, Chan, H, Wang, Y, Liu, B, Susac, L, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-05-06 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
Nature, 608, 2022
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3OXC
 | | Wild Type HIV-1 Protease with Antiviral Drug Saquinavir | | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, FORMIC ACID, Protease, ... | | 著者 | Kovalevsky, A.Y, Wang, Y.-F, Tie, Y, Weber, I.T. | | 登録日 | 2010-09-21 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir
Proteins, 67, 2007
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8G83
 | | Structure of NAD+ consuming protein Acinetobacter baumannii TIR domain | | 分子名称: | NAD(+) hydrolase AbTIR | | 著者 | Klontz, E.H, Wang, Y, Glendening, G, Carr, J, Tsibouris, T, Buddula, S, Nallar, S, Soares, A, Snyder, G.A. | | 登録日 | 2023-02-17 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | The structure of NAD + consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
J.Biol.Chem., 299, 2023
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1MOZ
 | | ADP-ribosylation factor-like 1 (ARL1) from Saccharomyces cerevisiae | | 分子名称: | ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE | | 著者 | Amor, J.C, Horton, J.R, Zhu, X, Wang, Y, Sullards, C, Ringe, D, Cheng, X, Kahn, R.A. | | 登録日 | 2002-09-10 | | 公開日 | 2002-10-09 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Structures of Yeast ARF2 and ARL1:
DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE
AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
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7V3L
 | | MERS S ectodomain trimer in complex with neutralizing antibody 6516 | | 分子名称: | Spike glycoprotein, antibody H, antibody L | | 著者 | Wang, X, Zhao, J, Wang, Z, Wang, Y, Zeng, J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 6516
to be published
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5XI7
 | | Crystal structure of T2R-TTL bound with PO-7 | | 分子名称: | (6Z)-3-[[2,5-bis(fluoranyl)phenyl]methylidene]-6-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Chu, Y, Wang, Y, Yang, J, Li, W. | | 登録日 | 2017-04-26 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
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7DDC
 | | Crystal structure of SARS-CoV-2 main protease in complex with Tafenoquine | | 分子名称: | 3C-like proteinase, Tafenoquine | | 著者 | Chen, Y, Wang, Y.C, Yang, C.S, Hung, M.C. | | 登録日 | 2020-10-28 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.175 Å) | | 主引用文献 | Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2.
J.Biol.Chem., 298, 2022
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5SWD
 | | Structure of the adenine riboswitch aptamer domain in an intermediate-bound state | | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ... | | 著者 | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | | 登録日 | 2016-08-08 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
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5XHC
 | | Crystal structure of T2R-TTL-PO10 complex | | 分子名称: | (3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(4-fluorophenyl)carbonylphenyl]methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Chu, Y, Wang, Y, Yang, J, Li, W. | | 登録日 | 2017-04-20 | | 公開日 | 2017-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
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8HNV
 | | CryoEM structure of HpaCas9-sgRNA-dsDNA in the presence of AcrIIC4 | | 分子名称: | CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, non-target strand, ... | | 著者 | Sun, W, Cheng, Z, Wang, J, Yang, X, Wang, Y. | | 登録日 | 2022-12-08 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7EN0
 | | Structure and Activity of SLAC1 Channels for Stomatal Signaling in Leaves | | 分子名称: | DIUNDECYL PHOSPHATIDYL CHOLINE, SLow Anion Channel 1, SPHINGOSINE | | 著者 | Deng, Y, Kashtoh, H, Wang, Q, Zhen, G, Li, Q, Tang, L, Gao, H, Zhang, C, Qin, L, Su, M, Li, F, Huang, X, Wang, Y, Xie, Q, Clarke, O.B, Hendrickson, W.A, Chen, Y. | | 登録日 | 2021-04-15 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structure and activity of SLAC1 channels for stomatal signaling in leaves.
Proc.Natl.Acad.Sci.USA, 118, 2021
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1FFM
 | | THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose | | 著者 | Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L. | | 登録日 | 1999-02-19 | | 公開日 | 1999-06-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
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5SWE
 | | Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography | | 分子名称: | ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain | | 著者 | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | | 登録日 | 2016-08-08 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
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1CFB
 | | CRYSTAL STRUCTURE OF TANDEM TYPE III FIBRONECTIN DOMAINS FROM DROSOPHILA NEUROGLIAN AT 2.0 ANGSTROMS | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DROSOPHILA NEUROGLIAN, ... | | 著者 | Huber, A.H, Wang, Y.E, Bieber, A.J, Bjorkman, P.J. | | 登録日 | 1994-08-27 | | 公開日 | 1994-11-30 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of tandem type III fibronectin domains from Drosophila neuroglian at 2.0 A.
Neuron, 12, 1994
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1F2E
 | | STRUCTURE OF SPHINGOMONAD, GLUTATHIONE S-TRANSFERASE COMPLEXED WITH GLUTATHIONE | | 分子名称: | GLUTATHIONE, GLUTATHIONE S-TRANSFERASE | | 著者 | Nishio, T, Watanabe, T, Patel, A, Wang, Y, Lau, P.C.K, Grochulski, P, Li, Y, Cygler, M. | | 登録日 | 2000-05-24 | | 公開日 | 2000-06-21 | | 最終更新日 | 2011-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Properties of a Sphingomonad and Marine Bacterium Beta-Class Glutathione S-Transferases and Crystal Structure of the Former Complex with Glutathione
To be published
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5XI5
 | | Crystal structure of T2R-TTL-PO5 complex | | 分子名称: | (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Chu, Y, Wang, Y, Yang, J, Li, W. | | 登録日 | 2017-04-26 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published
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5XWY
 | | Electron cryo-microscopy structure of LbuCas13a-crRNA binary complex | | 分子名称: | A type VI-A CRISPR-Cas RNA-guided RNA ribonuclease, Cas13a, RNA (59-MER) | | 著者 | Zhang, X, Wang, Y, Ma, J, Liu, L, Li, X, Li, Z, You, L, Wang, J, Wang, M. | | 登録日 | 2017-06-30 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell, 170, 2017
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6LYB
 | | PylRS C-terminus domain mutant in complex with 3-Benzothienyl-D-alanine and AMPNP | | 分子名称: | (2R)-2-azanyl-3-(1-benzothiophen-3-yl)propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2020-02-13 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.90366471 Å) | | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
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6LYA
 | | PylRS C-terminus domain mutant bound with 1-Methyl-L-tryptophan and AMPNP | | 分子名称: | 1,2-ETHANEDIOL, 1-Methyl-L-tryptophan, MAGNESIUM ION, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2020-02-13 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.590702 Å) | | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
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6LY6
 | | PylRS C-terminus domain mutant bound with 3-(1-Naphthyl)-L-alanine and AMPNP | | 分子名称: | MAGNESIUM ION, NAPHTHALEN-2-YL-3-ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Weng, J.H, Tsai, M.D, Wang, Y.S. | | 登録日 | 2020-02-13 | | 公開日 | 2020-07-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5001328 Å) | | 主引用文献 | Probing the Active Site of Deubiquitinase USP30 with Noncanonical Tryptophan Analogues.
Biochemistry, 59, 2020
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7V5K
 | | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1) | | 分子名称: | 0722 H, 0722 L, Spike glycoprotein | | 著者 | Wang, X, Zhao, J, Wang, Z, Zeng, J, Zhang, S, Wang, Y. | | 登録日 | 2021-08-17 | | 公開日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | MERS S ectodomain trimer in complex with neutralizing antibody 0722 (state 1)
to be published
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1FF7
 | | THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, 20 STRUCTURES | | 分子名称: | PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose | | 著者 | Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L. | | 登録日 | 1999-02-19 | | 公開日 | 1999-06-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
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