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5XI5

Crystal structure of T2R-TTL-PO5 complex

Summary for 5XI5
Entry DOI10.2210/pdb5xi5/pdb
DescriptorTubulin alpha chain, (3Z,6Z)-3-benzylidene-6-[(5-tert-butyl-1H-imidazol-4-yl)methylidene]piperazine-2,5-dione, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
Functional Keywordstubulin, microtubule, colchicine, stathmin, structural protein
Biological sourceRattus norvegicus (Rat)
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Cellular locationCytoplasm, cytoskeleton : A0A0R4I993 A0A0R4I995
Golgi apparatus : P63043
Total number of polymer chains6
Total formula weight269897.16
Authors
Chu, Y.,Wang, Y.,Yang, J.,Li, W. (deposition date: 2017-04-26, release date: 2017-10-18, Last modification date: 2024-03-27)
Primary citationChu, Y.,Wang, Y.,Yang, J.,Li, W.
Synthesis, biological evaluation and X-ray structure of anti-microtubule agents
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.81 Å)
Structure validation

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PDB entries from 2024-04-17

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