Summary for 3OXC
| Entry DOI | 10.2210/pdb3oxc/pdb |
| Related | 2IEN 2NMY 2NMZ 2NNK 2NNP 3CYX 3D1X 3D1Y 3MWS 3NU3 |
| Related PRD ID | PRD_000454 |
| Descriptor | Protease, (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, FORMIC ACID, ... (5 entities in total) |
| Functional Keywords | enzyme inhibition, aspartic protease, hiv/aids, saquinavir, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 2 |
| Total formula weight | 22436.37 |
| Authors | Kovalevsky, A.Y.,Wang, Y.-F.,Tie, Y.,Weber, I.T. (deposition date: 2010-09-21, release date: 2010-11-10, Last modification date: 2023-09-06) |
| Primary citation | Kovalevsky, A.Y.,Wang, Y.-F.,Tie, Y.,Weber, I.T. Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir Proteins, 67:232-242, 2007 Cited by PubMed: 17243183PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.16 Å) |
Structure validation
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