7YCV
 
 | |
7YCW
 | |
7YCS
 | |
7YCU
 | |
3ZH9
 | | Bacillus subtilis DNA clamp loader delta protein (YqeN) | | 分子名称: | DELTA, GLYCEROL, SULFATE ION | | 著者 | Suwannachart, C, Sedelnikova, S, Soultanas, P, Oldham, N.J, Rafferty, J.B. | | 登録日 | 2012-12-20 | | 公開日 | 2013-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights Into the Structure and Assembly of the Bacillus Subtilis Clamp-Loader Complex and its Interaction with the Replicative Helicase.
Nucleic Acids Res., 41, 2013
|
|
7XDG
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor MDSA | | 分子名称: | 5-[(3-carboxy-4-oxidanyl-phenyl)methyl]-2-oxidanyl-benzoic acid, NAD-dependent malic enzyme, mitochondrial, ... | | 著者 | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | 登録日 | 2022-03-27 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
|
|
7XDF
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in a ternary complex with NAD+ and allosteric inhibitor EA | | 分子名称: | 4-[(3-carboxy-2-oxidanyl-naphthalen-1-yl)methyl]-3-oxidanyl-naphthalene-2-carboxylic acid, NAD-dependent malic enzyme, mitochondrial, ... | | 著者 | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | 登録日 | 2022-03-27 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-05-31 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
|
|
7XDE
 | | Cryo-EM structures of human mitochondrial NAD(P)+-dependent malic enzyme in apo form | | 分子名称: | NAD-dependent malic enzyme, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Wang, C.H, Hsieh, J.T, Ho, M.C, Hung, H.C. | | 登録日 | 2022-03-26 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | | 主引用文献 | Suppression of the human malic enzyme 2 modifies energy metabolism and inhibits cellular respiration
Commun Biol, 6, 2023
|
|
2KVX
 | | Solution structure of kalata B12 | | 分子名称: | Kalata-B12 | | 著者 | Wang, C.K. | | 登録日 | 2010-03-29 | | 公開日 | 2011-03-09 | | 最終更新日 | 2016-06-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant.
Biochemistry, 50, 2011
|
|
7YAN
 | |
7ZEA
 | |
2K7G
 | | Solution Structure of varv F | | 分子名称: | Varv peptide F | | 著者 | Wang, C.K. | | 登録日 | 2008-08-10 | | 公開日 | 2009-02-10 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold
J.Biol.Chem., 284, 2009
|
|
2KHB
 | |
7WN1
 | | Structure of PfNT1(Y190A) in complex with nanobody 48 and inosine | | 分子名称: | Equilibrative nucleoside/nucleobase transporter, INOSINE, nanobody48 | | 著者 | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | | 登録日 | 2022-01-17 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
|
|
7ZCZ
 | |
7ZHI
 | |
7ZP2
 | | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with BDA-04 | | 分子名称: | Aspartate carbamoyltransferase, SODIUM ION, SULFATE ION, ... | | 著者 | Wang, C, Zhang, B, Groves, M.R. | | 登録日 | 2022-04-26 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | | 主引用文献 | Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
|
|
7ZGS
 | |
7ZST
 | | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum in complex with FLA-01 | | 分子名称: | 2-azanyl-~{N}-(2-methoxyethyl)-5-phenyl-thiophene-3-carboxamide, Aspartate carbamoyltransferase, GLYCEROL, ... | | 著者 | Wang, C, Zhang, B, Groves, M.R. | | 登録日 | 2022-05-08 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Small-Molecule Allosteric Inhibitors of Pf ATC as Antimalarials.
J.Am.Chem.Soc., 144, 2022
|
|
7ZID
 | |
7YEN
 | |
7YDQ
 | | Structure of PfNT1(Y190A)-GFP in complex with GSK4 | | 分子名称: | 5-methyl-N-[2-(2-oxidanylideneazepan-1-yl)ethyl]-2-phenyl-1,3-oxazole-4-carboxamide, Nucleoside transporter 1,Green fluorescent protein | | 著者 | Wang, C, Yu, L.Y, Li, J.L, Ren, R.B, Deng, D. | | 登録日 | 2022-07-04 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
|
|
7WN0
 | | Structure of PfENT1(Y190A) in complex with nanobody 19 | | 分子名称: | Equilibrative nucleoside/nucleobase transporter, nanobody19 | | 著者 | Wang, C, Deng, D, Ren, R.B, Yu, L.Y. | | 登録日 | 2022-01-17 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1.
Nat Commun, 14, 2023
|
|
7V6G
 | | Structure of Candida albicans Fructose-1,6-bisphosphate aldolase mutation C157S with CN39 | | 分子名称: | 1,2-ETHANEDIOL, Fructose-bisphosphate aldolase, ZINC ION, ... | | 著者 | Cao, H, Huang, Y, Chen, H, Wan, C, Ren, Y, Wan, J. | | 登録日 | 2021-08-20 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | | 主引用文献 | Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis.
J.Med.Chem., 65, 2022
|
|
4EOT
 | | Crystal structure of the MafA homodimer bound to the consensus MARE | | 分子名称: | 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', SULFATE ION, ... | | 著者 | Lu, X, Guanga, G, Wan, C, Rose, R.B. | | 登録日 | 2012-04-15 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.855 Å) | | 主引用文献 | A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities.
Biochemistry, 51, 2012
|
|
