6RJM
 
 | | Complex structure of virulence factor SghA and its hydrolysis product glucose | | 分子名称: | Beta-glucosidase, alpha-D-glucopyranose | | 著者 | Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G. | | 登録日 | 2019-04-27 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.112 Å) | | 主引用文献 | Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4WXB
 | | Crystal Structure of Serine Hydroxymethyltransferase from Streptococcus thermophilus | | 分子名称: | CACODYLATE ION, CITRIC ACID, GLYCEROL, ... | | 著者 | Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. | | 登録日 | 2014-11-13 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids.
Angew.Chem.Int.Ed.Engl., 54, 2015
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6FBA
 | | Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2,3-naphthalenediol | | 分子名称: | Aspartate transcarbamoylase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | 著者 | Lunev, S, Bosch, S.S, Batista, F.A, Wang, C, Wrenger, C, Groves, M.R. | | 登録日 | 2017-12-18 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem. Biophys. Res. Commun., 497, 2018
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6RK2
 | | Complex structure of virulence factor SghA mutant with its substrate SAG | | 分子名称: | 2-(alpha-L-altropyranosyloxy)benzoic acid, Beta-glucosidase | | 著者 | Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G. | | 登録日 | 2019-04-30 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Proc.Natl.Acad.Sci.USA, 116, 2019
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7U15
 | | TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U16
 | | TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U17
 | | TMEM106B(120-254) T185S singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U11
 | | TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U10
 | | TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U13
 | | TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U12
 | | TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U18
 | | TMEM106B(120-254) T185S protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TMEM106B protein | | 著者 | Fitzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-20 | | 公開日 | 2022-03-23 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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7U0Z
 | | High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1 | | 分子名称: | Isoform Tau-E of Microtubule-associated protein tau | | 著者 | FItzpatrick, A.W.P, Stowell, M.H.B, Chang, A, Xiang, X, Wang, J, Lee, C, Arakhamia, T, Simjanoska, M, Wang, C, Carlomagno, Y, Zhang, G, Dhingra, S, Thierry, M, Perneel, J, Heeman, B, Forgrave, L.M, DeTure, M, DeMarco, M.L, Cook, C.N, Rademakers, R, Dickson, D, Petrucelli, L, Mackenzie, I.R.A. | | 登録日 | 2022-02-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Cell, 185, 2022
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6RJO
 | | Complex structure of virulence factor SghA with its substrate analog salicin | | 分子名称: | 2-(hydroxymethyl)phenyl beta-D-glucopyranoside, Beta-glucosidase | | 著者 | Ye, F.Z, Wang, C, Chang, C.Q, Zhang, L.H, Gao, Y.G. | | 登録日 | 2019-04-28 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | | 主引用文献 | Agrobacteria reprogram virulence gene expression by controlled release of host-conjugated signals.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4RWS
 | | Crystal structure of CXCR4 and viral chemokine antagonist vMIP-II complex (PSI Community Target) | | 分子名称: | C-X-C chemokine receptor type 4/Endolysin chimeric protein, Viral macrophage inflammatory protein 2 | | 著者 | Qin, L, Kufareva, I, Holden, L, Wang, C, Zheng, Y, Wu, H, Fenalti, G, Han, G.W, Cherezov, V, Abagyan, R, Stevens, R.C, Handel, T.M, GPCR Network (GPCR) | | 登録日 | 2014-12-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine.
Science, 347, 2015
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4WXG
 | | Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine | | 分子名称: | GLYCEROL, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine, SODIUM ION, ... | | 著者 | Hernandez, K, Zelen, I, Petrillo, G, Uson, I, Wandtke, C, Bujons, J, Joglar, J, Parella, T, Clapes, P. | | 登録日 | 2014-11-13 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Engineered L-Serine Hydroxymethyltransferase from Streptococcus thermophilus for the Synthesis of alpha , alpha-Dialkyl-alpha-Amino Acids.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4RQE
 | | human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SERINE, Serine--tRNA ligase, ... | | 著者 | Xie, W, Wang, C, Guo, Y, Tian, Q, Jia, Q. | | 登録日 | 2014-11-03 | | 公開日 | 2015-11-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | SerRS-tRNASec complex structures reveal mechanism of the first step in selenocysteine biosynthesis.
Nucleic Acids Res., 43, 2015
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1WAF
 | | DNA POLYMERASE FROM BACTERIOPHAGE RB69 | | 分子名称: | DNA POLYMERASE, GUANOSINE | | 著者 | Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A. | | 登録日 | 1997-04-13 | | 公開日 | 1998-01-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.
Cell(Cambridge,Mass.), 89, 1997
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1WAJ
 | | DNA POLYMERASE FROM BACTERIOPHAGE RB69 | | 分子名称: | DNA POLYMERASE, GUANOSINE-5'-MONOPHOSPHATE | | 著者 | Wang, J, Satter, A.K.M.A, Wang, C.C, Karam, J.D, Konigsberg, W.H, Steitz, T.A. | | 登録日 | 1997-04-13 | | 公開日 | 1998-01-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.
Cell(Cambridge,Mass.), 89, 1997
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4V3D
 | | The CIDRa domain from HB3var03 PfEMP1 bound to endothelial protein C receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | | 著者 | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | | 登録日 | 2014-10-17 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
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4ROW
 | | The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA | | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | 著者 | Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C. | | 登録日 | 2014-10-29 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
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4ROV
 | | The crystal structure of novel APOBEC3G CD2 head-to-tail dimer suggests the binding mode of full-length APOBEC3G to HIV-1 ssDNA | | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | | 著者 | Lu, X, Zhang, T, Xu, Z, Liu, S, Zhao, B, Lan, W, Wang, C, Ding, J, Cao, C. | | 登録日 | 2014-10-29 | | 公開日 | 2014-12-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of DNA cytidine deaminase ABOBEC3G catalytic deamination domain suggests a binding mode of full-length enzyme to single-stranded DNA
J.Biol.Chem., 290, 2015
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1T7B
 | | Crystal structure of mutant Lys8Gln of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | | 分子名称: | Alpha-like neurotoxin BmK-I | | 著者 | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | | 登録日 | 2004-05-09 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
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1T7A
 | | Crystal structure of mutant Lys8Asp of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | | 分子名称: | Alpha-like neurotoxin BmK-I | | 著者 | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | | 登録日 | 2004-05-08 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
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6PC1
 | | Crystal structure of Helicobacter pylori PPX/GppA (E143A) in complex with ppGpp | | 分子名称: | (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, ... | | 著者 | Song, H, Wang, C, Shaw, G.X, Ji, X. | | 登録日 | 2019-06-15 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structure and activity of PPX/GppA homologs from Escherichia coli and Helicobacter pylori.
Febs J., 287, 2020
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