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PDB: 578 results

1D0J
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BU of 1d0j by Molmil
STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A M4-1BB PEPTIDE
Descriptor: 4-1BB LIGAND RECEPTOR, TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2
Authors:Ye, H, Park, Y.C, Kreishman, M, Kieff, E, Wu, H.
Deposit date:1999-09-10
Release date:2000-03-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis for the recognition of diverse receptor sequences by TRAF2.
Mol.Cell, 4, 1999
1CZY
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BU of 1czy by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE TRAF DOMAIN OF HUMAN TRAF2 AND AN LMP1 BINDING PEPTIDE
Descriptor: LATENT MEMBRANE PROTEIN 1, TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2
Authors:Ye, H, Park, Y.C, Kreishman, M, Kieff, E, Wu, H.
Deposit date:1999-09-07
Release date:2000-03-08
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis for the recognition of diverse receptor sequences by TRAF2.
Mol.Cell, 4, 1999
6IMQ
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BU of 6imq by Molmil
Crystal structure of PML B1-box multimers
Descriptor: CHLORIDE ION, Protein PML, ZINC ION
Authors:Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G.
Deposit date:2018-10-23
Release date:2019-07-31
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis.
Nat Commun, 10, 2019
1CZZ
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STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A 17-RESIDUE CD40 PEPTIDE
Descriptor: CD 40 PEPTIDE, TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PROTEIN 2
Authors:Ye, H, Park, Y.C, Kreishman, M, Kieff, E, Wu, H.
Deposit date:1999-09-07
Release date:2000-03-08
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for the recognition of diverse receptor sequences by TRAF2.
Mol.Cell, 4, 1999
7Q20
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BU of 7q20 by Molmil
Ruminococcus gnavus ATC29149 endo-beta-1,4-galactosidase (RgGH98) in complex with blood group A trisaccharide
Descriptor: CALCIUM ION, MAGNESIUM ION, Ruminococcus gnavus endogalactosidase GH98, ...
Authors:Owen, C.D, Wu, H, Crost, E.H, van Bakel, W, Gascuena, A.M, Latousakis, D, Hicks, T, Walpole, S, Urbanowicz, P.A, Ndeh, D, Monaco, S, Salom, L.S, Griffiths, R, Colvile, A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
Deposit date:2021-10-22
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract.
Plos Biol., 19, 2021
7PMO
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Ruminococcus gnavus ATC29149 endo-beta-1,4-galactosidase (RgGH98)
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Owen, C.D, Wu, H, Crost, E.H, van Bakel, W, Gascuena, A.M, Latousakis, D, Hicks, T, Walpole, S, Urbanowicz, P.A, Ndeh, D, Monaco, S, Salom, L.S, Griffiths, R, Colvile, A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
Deposit date:2021-09-02
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract.
Plos Biol., 19, 2021
7Q1W
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BU of 7q1w by Molmil
Ruminococcus gnavus ATC29149 endo-beta-1,4-galactosidase (RgGH98) E411A in complex with blood group A (BgA II) tetrasaccharide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ...
Authors:Owen, C.D, Wu, H, Crost, E.H, van Bakel, W, Gascuena, A.M, Latousakis, D, Hicks, T, Walpole, S, Urbanowicz, P.A, Ndeh, D, Monaco, S, Salom, L.S, Griffiths, R, Colvile, A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
Deposit date:2021-10-21
Release date:2022-03-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract.
Plos Biol., 19, 2021
6NPY
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BU of 6npy by Molmil
Cryo-EM structure of NLRP3 bound to NEK7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 3, ...
Authors:Sharif, H, Wang, L, Wang, W.L, Wu, H.
Deposit date:2019-01-18
Release date:2019-06-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome.
Nature, 570, 2019
6WLW
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BU of 6wlw by Molmil
The Vo region of human V-ATPase in state 1 (focused refinement)
Descriptor: (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, L, Wu, H, Fu, T.-M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
7LFH
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Cryo-EM structure of NLRP3 double-ring cage, 6-fold (12-mer)
Descriptor: NACHT, LRR and PYD domains-containing protein 3
Authors:Andreeva, L, Rawson, S, Wu, H.
Deposit date:2021-01-17
Release date:2021-12-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation.
Cell, 184, 2021
4WRF
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BU of 4wrf by Molmil
Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Mannose
Descriptor: CALCIUM ION, CHLORIDE ION, HEXANE-1,6-DIOL, ...
Authors:Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X.
Deposit date:2014-10-23
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
To be published
6WLZ
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The V1 region of human V-ATPase in state 1 (focused refinement)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SidK, V-type proton ATPase catalytic subunit A, ...
Authors:Wang, L, Wu, H, Fu, T.M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
7TDZ
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BU of 7tdz by Molmil
Cryo-EM model of protomer of the cytoplasmic ring of the nuclear pore complex from Xenopus laevis
Descriptor: Nuclear pore complex protein, Nuclear pore complex protein Nup85, Nuclear pore complex protein Nup96, ...
Authors:Fontana, P, Wu, H.
Deposit date:2022-01-03
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold.
Science, 376, 2022
1DIB
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BU of 1dib by Molmil
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY345899
Descriptor: 4-(7-AMINO-9-HYDROXY-1-OXO-3,3A,4,5-TETRAHYDRO-2,5,6,8,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALEN-2-YL)-PHENYLCARBONYL-GLUTAMI C ACID, METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Schmidt, A, Wu, H, MacKenzie, R.E, Chen, V.J, Bewly, J.R, Ray, J.E, Toth, J.E, Cygler, M.
Deposit date:1999-11-29
Release date:2000-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
1DIA
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BU of 1dia by Molmil
HUMAN METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE COMPLEXED WITH NADP AND INHIBITOR LY249543
Descriptor: METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [[[2-AMINO-5,6,7,8-TETRAHYDRO-4-HYDROXY-PYRIDO[2,3-D]PYRIMIDIN-6-YL]-ETHYL]-PHENYL]-CARBONYL-GLUTAMIC ACID
Authors:Schmidt, A, Wu, H, MacKenzie, R.E, Chen, V.J, Bewly, J.R, Ray, J.E, Toth, J.E, Cygler, M.
Deposit date:1999-11-29
Release date:2000-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of three inhibitor complexes provide insight into the reaction mechanism of the human methylenetetrahydrofolate dehydrogenase/cyclohydrolase.
Biochemistry, 39, 2000
7LF6
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BU of 7lf6 by Molmil
Structure of lysosomal membrane protein
Descriptor: Endosomal/lysosomal potassium channel TMEM175
Authors:Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
Deposit date:2021-01-15
Release date:2022-01-26
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:pH regulates potassium conductance and drives a constitutive proton current in human TMEM175.
Sci Adv, 8, 2022
8CXO
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BU of 8cxo by Molmil
Cryo-EM structure of the unliganded mSMO-PGS2 in a lipidic environment
Descriptor: CHOLESTEROL, Smoothened homolog, GlgA glycogen synthase chimera
Authors:Zhang, K, Wu, H, Hoppe, N, Manglik, A, Cheng, Y.
Deposit date:2022-05-22
Release date:2022-08-03
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Fusion protein strategies for cryo-EM study of G protein-coupled receptors.
Nat Commun, 13, 2022
6SCX
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BU of 6scx by Molmil
Crystal structure of the catalytic domain of human NUDT12 in complex with 7-methyl-guanosine-5'-triphosphate
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CADMIUM ION, Peroxisomal NADH pyrophosphatase NUDT12
Authors:McCarthy, A.A, Chen, K.M, Wu, H, Li, L, Homolka, D, Gos, P, Fleury-Olela, F, Pillai, R.S.
Deposit date:2019-07-25
Release date:2020-01-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.
Cell Rep, 29, 2019
8E4Y
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BU of 8e4y by Molmil
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, Glycerol-3-phosphate acyltransferase 1, mitochondrial, ...
Authors:Johnson, Z.L, Wasilko, D.J, Ammirati, M, Chang, J.S, Han, S, Wu, H.
Deposit date:2022-08-19
Release date:2022-12-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
8E50
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BU of 8e50 by Molmil
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA
Descriptor: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, COENZYME A, Glycerol-3-phosphate acyltransferase 1, ...
Authors:Wasilko, D.J, Johnson, Z.L, Ammirati, M, Chang, J.S, Han, S, Wu, H.
Deposit date:2022-08-19
Release date:2022-12-21
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
4WRC
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BU of 4wrc by Molmil
Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)
Descriptor: CALCIUM ION, CHLORIDE ION, HEXANE-1,6-DIOL, ...
Authors:Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X.
Deposit date:2014-10-23
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
to be published
4WRE
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BU of 4wre by Molmil
Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Inositol
Descriptor: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, CALCIUM ION, CHLORIDE ION, ...
Authors:Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X.
Deposit date:2014-10-23
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
To be published
4QPP
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BU of 4qpp by Molmil
The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE
Descriptor: 2-{4-[3-chloro-2-(2-methoxyphenyl)-1H-indol-5-yl]piperidin-1-yl}-N-methylethanamine, POLY-UNK, Protein arginine N-methyltransferase 6, ...
Authors:Dong, A, Zeng, H, Smil, D, Walker, J.R, He, H, Eram, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2014-06-24
Release date:2014-08-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421
To be Published
8E4C
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BU of 8e4c by Molmil
IgM BCR fab truncated form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ...
Authors:Dong, Y, Pi, X, Wu, H, Reth, M.
Deposit date:2022-08-18
Release date:2022-11-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural principles of B cell antigen receptor assembly.
Nature, 612, 2022
1CA9
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BU of 1ca9 by Molmil
STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 IN COMPLEX WITH A PEPTIDE FROM TNF-R2
Descriptor: PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2), PROTEIN (TNF-R2)
Authors:Park, Y.C, Burkitt, V, Villa, A.R, Tong, L, Wu, H.
Deposit date:1999-02-25
Release date:1999-04-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for self-association and receptor recognition of human TRAF2.
Nature, 398, 1999

221716

数据于2024-06-26公开中

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