7LF6
Structure of lysosomal membrane protein
Summary for 7LF6
| Entry DOI | 10.2210/pdb7lf6/pdb |
| Related | 6W8N 6W8P |
| EMDB information | 23300 |
| Descriptor | Endosomal/lysosomal potassium channel TMEM175 (1 entity in total) |
| Functional Keywords | channel, membrane protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 111334.44 |
| Authors | Shen, C.,Fu, T.M.,Wang, L.F.,Rawson, S.,Wu, H. (deposition date: 2021-01-15, release date: 2022-01-26, Last modification date: 2023-08-09) |
| Primary citation | Zheng, W.,Shen, C.,Wang, L.,Rawson, S.,Xie, W.J.,Nist-Lund, C.,Wu, J.,Shen, Z.,Xia, S.,Holt, J.R.,Wu, H.,Fu, T.M. pH regulates potassium conductance and drives a constitutive proton current in human TMEM175. Sci Adv, 8:eabm1568-eabm1568, 2022 Cited by PubMed: 35333573DOI: 10.1126/sciadv.abm1568 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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