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PDB: 887 件
4K3Y
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Crystal structure of a subtype N11 neuraminidase-like protein of A/flat-faced bat/Peru/033/2010 (H18N11)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2013-04-11
公開日2013-10-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.682 Å)
主引用文献New world bats harbor diverse influenza a viruses.
Plos Pathog., 9, 2013
4M5Z
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BU of 4m5z by Molmil
Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit
分子名称: Fab 5J8 heavy chain, Fab 5J8 light chain, Hemagglutinin HA1 chain
著者Hong, M, Lee, P.S, Wilson, I.A.
登録日2013-08-08
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site.
J.Virol., 87, 2013
4N63
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BU of 4n63 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with an O-linked glycan receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-11
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7522 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4MWF
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BU of 4mwf by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Kong, L, Wilson, I.A, Law, M.
登録日2013-09-24
公開日2013-12-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.645 Å)
主引用文献Hepatitis C virus e2 envelope glycoprotein core structure.
Science, 342, 2013
4N5J
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BU of 4n5j by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-10
公開日2013-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4RNR
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BU of 4rnr by Molmil
Crystal structure of broadly neutralizing anti-HIV antibody PGT130
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain
著者Kong, L, Wilson, I.A.
登録日2014-10-24
公開日2014-11-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
4RQS
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BU of 4rqs by Molmil
Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab
分子名称: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A, Kwong, P.D.
登録日2014-11-05
公開日2014-12-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.493 Å)
主引用文献Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
4N64
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BU of 4n64 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a biantennary glycan receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-11
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7014 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4M43
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BU of 4m43 by Molmil
Crystal structure of anti-rabies glycoprotein Fab 523-11
分子名称: Fragment antigen-binding 523-11 heavy chain, Fragment antigen-binding 523-11 light chain, GLYCEROL, ...
著者Stanfield, R.L, Wilson, I.A, Wunner, W.H.
登録日2013-08-06
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of anti-rabies glycoprotein Fab 523-11
To be Published
4MHI
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BU of 4mhi by Molmil
Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Zhu, X, Wilson, I.A.
登録日2013-08-29
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.595 Å)
主引用文献A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4MZA
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BU of 4mza by Molmil
Crystal structure of hPIV3 hemagglutinin-neuraminidase
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xu, R, Wilson, I.A.
登録日2013-09-29
公開日2013-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo.
MBio, 4, 2013
4N5Y
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BU of 4n5y by Molmil
Crystal structure of H5 hemagglutinin mutant (N158D, N224K and Q226L) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Zhu, X, Wilson, I.A.
登録日2013-10-10
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1615 Å)
主引用文献Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses.
J.Virol., 88, 2014
4N5Z
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BU of 4n5z by Molmil
Crystal structure of aerosol transmissible influenza H5 hemagglutinin mutant (N158D, N224K, Q226L and T318I) from the influenza virus A/Viet Nam/1203/2004 (H5N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Zhu, X, Wilson, I.A.
登録日2013-10-10
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9537 Å)
主引用文献Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses.
J.Virol., 88, 2014
4K3G
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BU of 4k3g by Molmil
Immunoglobulin lambda variable domain L5(L89S) fluorogen activating protein
分子名称: alpha-D-mannopyranose, immunoglobulin lambda variable domain L5(L89S)
著者Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A.
登録日2013-04-10
公開日2013-10-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
J.Mol.Biol., 425, 2013
4NGH
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BU of 4ngh by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41 and a tethered phosphate moiety.
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41)
著者Irimia, A, Wilson, I.A.
登録日2013-11-01
公開日2014-12-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
4NCO
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BU of 4nco by Molmil
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP gp120, BG505 SOSIP gp41, ...
著者Julien, J.-P, Stanfield, R.L, Lyumkis, D, Ward, A.B, Wilson, I.A.
登録日2013-10-24
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Crystal structure of a soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
4NJ9
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BU of 4nj9 by Molmil
Crystal structure of Fab 8B10 in complex with MPTS
分子名称: 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
4NPY
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BU of 4npy by Molmil
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
著者Julien, J.-P, Diwanji, D.C, Wilson, I.A.
登録日2013-11-22
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
4N0Y
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BU of 4n0y by Molmil
Structure of the Hepatitis C Envelope Glycoprotein E1 antigenic region 314-324 bound to the cross-neutralizing antibody IGH526
分子名称: CHLORIDE ION, GLYCEROL, HCV E1 peptide, ...
著者Kong, L, Wilson, I.A.
登録日2013-10-02
公開日2015-04-01
最終更新日2015-08-26
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526.
J.Mol.Biol., 427, 2015
4NHC
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BU of 4nhc by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41.
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41), ...
著者Irimia, A, Wilson, I.A.
登録日2013-11-04
公開日2014-12-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.912 Å)
主引用文献Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
4NJA
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BU of 4nja by Molmil
Crystal structure of Fab 6C8 in complex with MPTS
分子名称: 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ...
著者Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
登録日2013-11-08
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
4NWU
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BU of 4nwu by Molmil
Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1
分子名称: APE1551 Ab Fab heavy chain, APE1551 Ab Fab light chain
著者Verdino, P, Stanfield, R.L, Wilson, I.A.
登録日2013-12-06
公開日2014-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J.Biol.Chem., 289, 2014
4NUG
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BU of 4nug by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT151
分子名称: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
著者Blattner, C, Wilson, I.A.
登録日2013-12-03
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8617 Å)
主引用文献Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4N60
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BU of 4n60 by Molmil
Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with LSTc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-11
公開日2013-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9032 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013
4N62
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Crystal structure of hemagglutinin from an H7N9 influenza virus in complex with a sulfated receptor analog
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
著者Xu, R, Wilson, I.A.
登録日2013-10-11
公開日2013-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5026 Å)
主引用文献Preferential recognition of avian-like receptors in human influenza A H7N9 viruses.
Science, 342, 2013

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