4N0Y

Structure of the Hepatitis C Envelope Glycoprotein E1 antigenic region 314-324 bound to the cross-neutralizing antibody IGH526

Summary for 4N0Y

• Entry DOI: 10.2210/pdb4n0y/pdb
• Descriptor: IGH526 Heavy Chain, IGH526 Light Chain, HCV E1 peptide, ... (6 entities in total)
• Functional Keywords: immunoglobulin fold, amidated c-terminus, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 49462.46

Authors

Kong, L.,Wilson, I.A. (deposition date: 2013-10-02, release date: 2015-04-01, Last modification date: 2015-08-26)

• Primary citation: Kong, L.,Kadam, R.U.,Giang, E.,Ruwona, T.B.,Nieusma, T.,Culhane, J.C.,Stanfield, R.L.,Dawson, P.E.,Wilson, I.A.,Law, M.; Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526.; J.Mol.Biol., 427:2617-2628, 2015; PubMed: 26135247; DOI: 10.1016/j.jmb.2015.06.012

Experimental method

X-RAY DIFFRACTION (1.749 Å)