4MZA

Crystal structure of hPIV3 hemagglutinin-neuraminidase

Summary for 4MZA

• Entry DOI: 10.2210/pdb4mza/pdb
• Related: 4MZE
• Descriptor: Hemagglutinin-neuraminidase, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: viral envelope protein, viral fusion protein, hydrolase
• Biological source: Human parainfluenza 3 virus (HPIV-3)
• Cellular location: Virion membrane ; Single-pass type II membrane protein : P08492
• Total number of polymer chains: 2
• Total formula weight: 102087.71

Authors

Xu, R.,Wilson, I.A. (deposition date: 2013-09-29, release date: 2013-11-06, Last modification date: 2020-07-29)

• Primary citation: Xu, R.,Palmer, S.G.,Porotto, M.,Palermo, L.M.,Niewiesk, S.,Wilson, I.A.,Moscona, A.; Interaction between the hemagglutinin-neuraminidase and fusion glycoproteins of human parainfluenza virus type III regulates viral growth in vivo.; MBio, 4:e00803-e00813, 2013; PubMed: 24149514; DOI: 10.1128/mBio.00803-13

Experimental method

X-RAY DIFFRACTION (1.653 Å)