4MZA

Crystal structure of hPIV3 hemagglutinin-neuraminidase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hemagglutinin-neuraminidase	polymer	437	48805.4	2	UniProt (P08492) Pfam (PF00423)	Human parainfluenza 3 virus (HPIV-3)
2	C (C)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1559.4	1	In PDB GlyTouCan (G36699PG)
3	D (D)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G22573RC)
4	E (E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	F (F)	beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	1	In PDB GlyTouCan (G61843VN)
6	G, H (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	I, N (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
8	J, L, M, R, S (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
9	K, Q (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
10	O, P (B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
11	T, U (A, B)	water	water		18.0	550	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97610.8
Branched	Number of molecules	4
	Total formula weight	3262.0
Non-Polymers*	Number of molecules	13
	Total formula weight	1215.0
All*	Total formula weight	102087.7

*Water molecules are not included.