7LMP
| Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 36 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-8-(1H-imidazole-4-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione] | Descriptor: | 3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-8-(1~{H}-imidazol-5-ylcarbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione, JTO light chain, PHOSPHATE ION | Authors: | Yan, N.L, Wilson, I.A, Kelly, J.W. | Deposit date: | 2021-02-05 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design. J.Med.Chem., 64, 2021
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7LMQ
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7LMN
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3P3S
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3P3U
| Human transthyretin (TTR) complexed with 5-(2-ethoxyphenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole | Descriptor: | 4-[5-(2-ethoxyphenyl)-1,2,4-oxadiazol-3-yl]pyridine, Transthyretin | Authors: | Connelly, S, Wilson, I.A. | Deposit date: | 2010-10-05 | Release date: | 2011-08-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity. Sci Transl Med, 3, 2011
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3P3T
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3P3R
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5CCK
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5CJQ
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5CJS
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5E2Y
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5E32
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5E99
| Bovine Fab fragment F08_B11 | Descriptor: | Fab F08_B11 heavy chain, Fab F08_B11 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2015-10-14 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Sci Immunol, 1, 2016
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1IAO
| CLASS II MHC I-AD IN COMPLEX WITH OVALBUMIN PEPTIDE 323-339 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-AD | Authors: | Scott, C.A, Peterson, P.A, Teyton, L, Wilson, I.A. | Deposit date: | 1998-03-13 | Release date: | 1998-11-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues. Immunity, 8, 1998
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5E34
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5E35
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2IGF
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5E30
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5E2Z
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5C7K
| Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ... | Authors: | Kong, L, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2015-06-24 | Release date: | 2015-10-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.6019 Å) | Cite: | Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer. Acta Crystallogr.,Sect.D, 71, 2015
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5CEX
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5BZD
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5BZW
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3MJ7
| Crystal structure of the complex of JAML and Coxsackie and Adenovirus receptor, CAR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coxsackievirus and adenovirus receptor homolog, ... | Authors: | Verdino, P, Wilson, I.A. | Deposit date: | 2010-04-12 | Release date: | 2010-09-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. Science, 329, 2010
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3MJ6
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