7U2E

Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADI-55688

Summary for 7U2E

Entry DOI	10.2210/pdb7u2e/pdb
Descriptor	Spike protein S1, ADI-55688 heavy chain, ADI-55688 light chain, ... (5 entities in total)
Functional Keywords	sars-cov-2, coronavirus, antibody, spike, rbd, immune system, viral protein-immune system complex, viral protein/immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	3
Total formula weight	71128.75
Authors	Yuan, M.,Zhu, X.,Wilson, I.A. (deposition date: 2022-02-23, release date: 2022-05-04, Last modification date: 2023-10-25)
Primary citation	Yuan, M.,Zhu, X.,He, W.T.,Zhou, P.,Kaku, C.I.,Capozzola, T.,Zhu, C.Y.,Yu, X.,Liu, H.,Yu, W.,Hua, Y.,Tien, H.,Peng, L.,Song, G.,Cottrell, C.A.,Schief, W.R.,Nemazee, D.,Walker, L.M.,Andrabi, R.,Burton, D.R.,Wilson, I.A. A broad and potent neutralization epitope in SARS-related coronaviruses. Proc.Natl.Acad.Sci.USA, 119:e2205784119-e2205784119, 2022 Cited by PubMed: 35767670 DOI: 10.1073/pnas.2205784119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation