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PDB: 901 件
4RBP
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BU of 4rbp by Molmil
Crystal structure of HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomanose
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, GLYCEROL, ...
著者Stanfield, R.L, Wilson, I.A, De Castro, C, Marzaioli, A.M, Pantophlet, R.
登録日2014-09-12
公開日2014-11-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose.
Glycobiology, 25, 2015
6KVF
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BU of 6kvf by Molmil
Structure of anti-hCXCR2 abN48 in complex with its CXCR2 epitope
分子名称: Peptide from C-X-C chemokine receptor type 2, heavy chain, light chain
著者Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
登録日2019-09-04
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
6KYZ
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BU of 6kyz by Molmil
HRV14 3C in complex with single chain antibody YDF
分子名称: Genome polyprotein, YDF H chain, YDF L chain
著者Meng, B, Yang, B, Wilson, I.A.
登録日2019-09-20
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献Inhibitory antibodies identify unique sites of therapeutic vulnerability in rhinovirus and other enteroviruses.
Proc.Natl.Acad.Sci.USA, 117, 2020
4RQQ
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BU of 4rqq by Molmil
Crystal structure of human Fab PGDM1400, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: Human anti-HIV-1 antibody PGDM1400 heavy chain, Human anti-HIV-1 antibody PGDM1400 light chain
著者Julien, J.-P, Wilson, I.A.
登録日2014-11-04
公開日2014-11-19
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex.
Proc.Natl.Acad.Sci.USA, 111, 2014
6PBW
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BU of 6pbw by Molmil
Crystal structure of Fab667 complex
分子名称: Fab667 heavy chain, Fab667 light chain, GLYCEROL, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.058 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
3LZF
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BU of 3lzf by Molmil
Crystal Structure of Fab 2D1 in Complex with the 1918 Influenza Virus Hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2D1 Fab, ...
著者Ekiert, D.C, Wilson, I.A.
登録日2010-03-01
公開日2010-04-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
4RNR
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BU of 4rnr by Molmil
Crystal structure of broadly neutralizing anti-HIV antibody PGT130
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PGT130 Heavy Chain, PGT130 Light Chain
著者Kong, L, Wilson, I.A.
登録日2014-10-24
公開日2014-11-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope.
J.Virol., 89, 2015
4RQS
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BU of 4rqs by Molmil
Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab
分子名称: 17b Fab Heavy Chain, 17b Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kong, L, Wilson, I.A, Kwong, P.D.
登録日2014-11-05
公開日2014-12-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.493 Å)
主引用文献Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262.
Proteins, 83, 2015
6MCO
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BU of 6mco by Molmil
Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P23 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-08-31
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.526 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6MG5
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BU of 6mg5 by Molmil
Structure of full-length human lambda-6A light chain JTO in complex with coumarin 1
分子名称: 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one, Light chain JTO, PHOSPHATE ION
著者Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
登録日2018-09-12
公開日2019-04-10
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PBV
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BU of 6pbv by Molmil
Crystal structure of Fab668 complex
分子名称: 1,2-ETHANEDIOL, Fab668 heavy chain, Fab668 light chain, ...
著者Oyen, D, Wilson, I.A.
登録日2019-06-14
公開日2020-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.566 Å)
主引用文献Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
Plos Pathog., 16, 2020
3MJ9
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BU of 3mj9 by Molmil
Crystal structure of JAML in complex with the stimulatory antibody HL4E10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Junctional adhesion molecule-like, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, ...
著者Verdino, P, Wilson, I.A.
登録日2010-04-12
公開日2011-02-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Molecular insights into gamma delta T cell costimulation by an anti-JAML antibody.
Structure, 19, 2011
6MDT
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BU of 6mdt by Molmil
Crystal structure of the B41 SOSIP.664 Env trimer with PGT124 and 35O22 Fabs, in P63 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab heavy chain, ...
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-09-05
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.816 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
3LZG
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BU of 3lzg by Molmil
Crystal structure of a 2009 H1N1 influenza virus hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Xu, R, Wilson, I.A.
登録日2010-03-01
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.
Science, 328, 2010
6Q1Z
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BU of 6q1z by Molmil
Crystal structure of human 1G04 Fab in complex with influenza virus neuraminidase from A/Hunan/02650/2016 (H7N9)
分子名称: 1G04 Fab IgG1 heavy chain, 1G04 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.446 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
6PZD
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BU of 6pzd by Molmil
Crystal structure of the neuraminidase stabilization mutant Y169aH from A/Shanghai/2/2013 (H7N9)
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZE
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BU of 6pze by Molmil
Crystal structure of human NA-45 Fab in complex with neuraminidase Y169aH mutant from A/Shanghai/2/2013 (H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, NA-45 FAB HEAVY CHAIN, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6PZF
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BU of 6pzf by Molmil
Crystal structure of human NA-63 Fab in complex with neuraminidase from A/Hunan/02650/2016(H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6ME1
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BU of 6me1 by Molmil
Crystal structure of the clade B isolate B41 mutant fusion peptide (residues 512-521) in complex with VRC34.01
分子名称: Envelope glycoprotein gp160, VRC34.01 Fab heavy chain, VRC34.01 Fab light chain
著者Kumar, S, Sarkar, A, Wilson, I.A.
登録日2018-09-05
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide.
Nat Commun, 10, 2019
6MG4
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BU of 6mg4 by Molmil
Structure of full-length human lambda-6A light chain JTO
分子名称: JTO light chain
著者Morgan, G.J, Yan, N.L, Mortenson, D.E, Stanfield, R.L, Wilson, I.A, Kelly, J.W.
登録日2018-09-12
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Stabilization of amyloidogenic immunoglobulin light chains by small molecules.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PZG
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BU of 6pzg by Molmil
Crystal structure of human NA-80 Fab
分子名称: NA-80 Fab heavy chain, NA-80 Fab light chain
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Q23
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BU of 6q23 by Molmil
Crystal structure of human 1G01 Fab in complex with influenza virus neuraminidase from A/California/04/2009 (H1N1)
分子名称: 1G01 Fab IgG1 heavy chain, 1G01 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
3MBE
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BU of 3mbe by Molmil
TCR 21.30 in complex with MHC class II I-Ag7HEL(11-27)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II H2-IAg7 ALPHA CHAIN, ...
著者Corper, A.L, Yoshida, K, Teyton, L, Wilson, I.A.
登録日2010-03-25
公開日2010-05-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.886 Å)
主引用文献The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity.
J.Clin.Invest., 120, 2010
6PZH
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BU of 6pzh by Molmil
Crystal structure of human NA-22 Fab
分子名称: NA-22 Fab heavy chain, NA-22 Fab light chain
著者Zhu, X, Wilson, I.A.
登録日2019-07-31
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6Q20
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BU of 6q20 by Molmil
Crystal structure of human 1E01 Fab in complex with influenza virus neuraminidase from A/Japan/305/1957 (H2N2)
分子名称: 1E01 Fab IgG1 heavy chain, 1E01 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019

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