6KVF

Structure of anti-hCXCR2 abN48 in complex with its CXCR2 epitope

Summary for 6KVF

Entry DOI	10.2210/pdb6kvf/pdb
Related	6KVA
Descriptor	heavy chain, light chain, Peptide from C-X-C chemokine receptor type 2, ... (4 entities in total)
Functional Keywords	antibody-antigen complex, immune system, cxcr2
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	98002.96
Authors	Xiang, J.C.,Yan, L.,Yang, B.,Wilson, I.A. (deposition date: 2019-09-04, release date: 2020-09-09, Last modification date: 2023-11-22)
Primary citation	Shi, X.,Wan, Y.,Wang, N.,Xiang, J.,Wang, T.,Yang, X.,Wang, J.,Dong, X.,Dong, L.,Yan, L.,Li, Y.,Liu, L.,Hou, S.,Zhong, Z.,Wilson, I.A.,Yang, B.,Yang, G.,Lerner, R.A. Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms. Nat Commun, 12:2547-2547, 2021 Cited by PubMed: 33953162 DOI: 10.1038/s41467-021-22810-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.79 Å)

Structure validation