5VFK
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5HBY
| RNA primer-template complex with 2-methylimidazole-activated monomer analogue-3 binding sites | 分子名称: | MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*C)-3'), [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-(3-methyl-1~{H}-pyrazol-4-yl)phosphinic acid | 著者 | Zhang, W, Tam, C.P, Wang, J, Szostak, J.W. | 登録日 | 2016-01-03 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Unusual Base-Pairing Interactions in Monomer-Template Complexes. ACS Cent Sci, 2, 2016
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2JYH
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2QD0
| Crystal structure of mitoNEET | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, Zinc finger CDGSH domain-containing protein 1 | 著者 | Lin, J, Zhou, T, Ye, K, Wang, J. | 登録日 | 2007-06-20 | 公開日 | 2007-08-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Crystal structure of human mitoNEET reveals distinct groups of iron sulfur proteins. Proc.Natl.Acad.Sci.Usa, 104, 2007
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4HYD
| Structure of a presenilin family intramembrane aspartate protease in C2221 space group | 分子名称: | Putative uncharacterized protein | 著者 | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | 登録日 | 2012-11-13 | 公開日 | 2012-12-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structure of a presenilin family intramembrane aspartate protease Nature, 493, 2013
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4HYC
| Structure of a presenilin family intramembrane aspartate protease in P2 space group | 分子名称: | Putative uncharacterized protein | 著者 | Li, X, Dang, S, Yan, C, Wang, J, Shi, Y. | 登録日 | 2012-11-13 | 公開日 | 2012-12-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | 主引用文献 | Structure of a presenilin family intramembrane aspartate protease Nature, 493, 2013
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4ILD
| Crystal structure of truncated Bovine viral diarrhea virus 1 E2 envelope protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein E2, ... | 著者 | Modis, Y, Li, Y, Wang, J. | 登録日 | 2012-12-30 | 公開日 | 2013-04-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | 主引用文献 | Crystal structure of glycoprotein E2 from bovine viral diarrhea virus. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IU9
| Crystal structure of a membrane transporter | 分子名称: | Nitrite extrusion protein 2 | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | 登録日 | 2013-01-20 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structure and mechanism of a nitrate transporter. Cell Rep, 3, 2013
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5YB1
| Structure and function of human serum albumin-metal agent complex | 分子名称: | PALMITIC ACID, Serum albumin, ~{N},~{N},12-trimethyl-3$l^{3}-thia-1$l^{4},5,6$l^{4}-triaza-2$l^{3}-cupratricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,6,9,11-pentaen-4-amine | 著者 | Yang, F, Wang, T, Wang, J, Gou, Y, Zhang, Z.L. | 登録日 | 2017-09-02 | 公開日 | 2018-09-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.616 Å) | 主引用文献 | Developing an Anticancer Copper(II) Multitarget Pro-Drug Based on the His146 Residue in the IB Subdomain of Modified Human Serum Albumin. Mol. Pharm., 15, 2018
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5YKI
| Crystal structure of the engineered nine-repeat PUF domain in complex with cognate 9nt-RNA | 分子名称: | Pumilio homolog 1, RNA (5'-R(*UP*GP*UP*UP*GP*UP*AP*UP*A)-3') | 著者 | Zhao, Y.Y, Wang, J, Li, H.T, Wang, Z.X, Wu, J.W. | 登録日 | 2017-10-14 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Expanding RNA binding specificity and affinity of engineered PUF domains. Nucleic Acids Res., 46, 2018
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5YKH
| Crystal structure of the engineered nine-repeat PUF domain | 分子名称: | PHOSPHATE ION, Pumilio homolog 1 | 著者 | Zhao, Y.Y, Wang, J, Li, H.T, Wang, Z.X, Wu, J.W. | 登録日 | 2017-10-14 | 公開日 | 2018-03-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.457 Å) | 主引用文献 | Expanding RNA binding specificity and affinity of engineered PUF domains. Nucleic Acids Res., 46, 2018
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7EQH
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5ZAM
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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4JNT
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5YZ0
| Cryo-EM Structure of human ATR-ATRIP complex | 分子名称: | ATR-interacting protein, Serine/threonine-protein kinase ATR | 著者 | Rao, Q, Liu, M, Tian, Y, Wu, Z, Wang, H, Wang, J, Xu, Y. | 登録日 | 2017-12-11 | 公開日 | 2018-01-31 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Cryo-EM structure of human ATR-ATRIP complex. Cell Res., 28, 2018
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7Y5X
| CryoEM structure of PS2-containing gamma-secretase treated with MRK-560 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2022-06-17 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. Nat Commun, 13, 2022
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7Y5T
| CryoEM structure of PS1-containing gamma-secretase in complex with MRK-560 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2022-06-17 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. Nat Commun, 13, 2022
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7Y5Z
| CryoEM structure of human PS2-containing gamma-secretase | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2022-06-18 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. Nat Commun, 13, 2022
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5ZAK
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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5ZAL
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2, RNA (73-mer) | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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4KMN
| Structure of cIAP1-BIR3 and inhibitor | 分子名称: | (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, Baculoviral IAP repeat-containing protein 2, PHOSPHATE ION, ... | 著者 | Li, X, Wang, J, Condon, S.M, Shi, Y. | 登録日 | 2013-05-08 | 公開日 | 2014-05-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.523 Å) | 主引用文献 | Structure of cIAP1-BIR3 and inhibitor To be Published
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5XKU
| Crystal structure of hemagglutinin globular head from an H7N9 influenza virus in complex with a neutralizing antibody HNIgGA6 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HNIgGA6 heavy chain, HNIgGA6 light chain, ... | 著者 | Chen, C, Wang, J, Wang, W, Gao, X, Cui, S, Jin, Q. | 登録日 | 2017-05-09 | 公開日 | 2017-11-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural Insight into a Human Neutralizing Antibody against Influenza Virus H7N9 J. Virol., 92, 2018
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4IU8
| Crystal structure of a membrane transporter (selenomethionine derivative) | 分子名称: | NITRATE ION, Nitrite extrusion protein 2 | 著者 | Yan, H, Huang, W, Yan, C, Gong, X, Jiang, S, Zhao, Y, Wang, J, Shi, Y. | 登録日 | 2013-01-20 | 公開日 | 2013-04-17 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structure and mechanism of a nitrate transporter. Cell Rep, 3, 2013
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4J2D
| RB69 DNA Polymerase L415K Ternary Complex | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | 著者 | Xia, S, Wang, J, Konigsberg, W.H. | 登録日 | 2013-02-04 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Role of L415 in the Replication of RB69 DNA Polymerase To be Published
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4KMP
| Structure of XIAP-BIR3 and inhibitor | 分子名称: | (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], E3 ubiquitin-protein ligase XIAP, ZINC ION | 著者 | Li, X, Wang, J, Condon, S.M, Shi, Y. | 登録日 | 2013-05-08 | 公開日 | 2014-05-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of XIAP-BIR3 and inhibitor To be Published
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