5VFK

Solution structure of an archaeal DUF61 family protein SSO0941

Summary for 5VFK

• Entry DOI: 10.2210/pdb5vfk/pdb
• Descriptor: Uncharacterized protein (1 entity in total)
• Functional Keywords: unknown function
• Biological source: Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
• Total number of polymer chains: 1
• Total formula weight: 17129.75

Authors

Zhou, T.,Wang, J.,Feng, Y. (deposition date: 2017-04-07, release date: 2018-03-21, Last modification date: 2024-05-15)

Primary citation

Zhou, T.,Yao, X.,Wang, J.,Feng, Y.
Solution structure of an archaeal DUF61 family protein SSO0941 encoded by a gene in the operon of box C/D RNA protein complexes.
J. Struct. Biol., 203:179-184, 2018

PubMed Abstract: Domain of unknown function 61 (DUF61) family proteins widely exist in archaea and the genes of DUF61 proteins in crenarchaea are in an operon containing two genes of box C/D RNA protein complexes. Here we report the solution NMR structure of DUF61 family member protein SSO0941, from the hyperthermophilic archaeon Sulfolobus solfataricus. SSO0941 has a rigid core structure and flexible N- and C-terminal regions as well as a negatively-charged independent C-terminal helix. The core structure consists of N- and C-terminal subdomains, in which the C-terminal subdomain shows significant structural similarity with several nucleic acid binding proteins. The structure of SSO0941 is the first representative structure of DUF61 family proteins.

PubMed: 29526782
DOI: 10.1016/j.jsb.2018.03.003

Experimental method

SOLUTION NMR