4KMN
Structure of cIAP1-BIR3 and inhibitor
Summary for 4KMN
Entry DOI | 10.2210/pdb4kmn/pdb |
Related | 4KMP |
Descriptor | Baculoviral IAP repeat-containing protein 2, ZINC ION, (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, ... (5 entities in total) |
Functional Keywords | apoptosis, ciap1-bir3, ligase-ligase inhibitor complex, ligase/ligase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q13490 |
Total number of polymer chains | 1 |
Total formula weight | 12789.70 |
Authors | Li, X.,Wang, J.,Condon, S.M.,Shi, Y. (deposition date: 2013-05-08, release date: 2014-05-14, Last modification date: 2023-11-08) |
Primary citation | Li, X.,Wang, J.,Condon, S.M.,Shi, Y. Structure of cIAP1-BIR3 and inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.523 Å) |
Structure validation
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