4KMP
Structure of XIAP-BIR3 and inhibitor
Summary for 4KMP
Entry DOI | 10.2210/pdb4kmp/pdb |
Related | 4KMN |
Descriptor | E3 ubiquitin-protein ligase XIAP, ZINC ION, (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], ... (4 entities in total) |
Functional Keywords | apoptosis, xiap-bir3, ligase-ligase inhibitor complex, ligase/ligase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P98170 |
Total number of polymer chains | 2 |
Total formula weight | 23557.14 |
Authors | Li, X.,Wang, J.,Condon, S.M.,Shi, Y. (deposition date: 2013-05-08, release date: 2014-05-14, Last modification date: 2023-11-08) |
Primary citation | Li, X.,Wang, J.,Condon, S.M.,Shi, Y. Structure of XIAP-BIR3 and inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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