1XFR
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1DQE
| BOMBYX MORI PHEROMONE BINDING PROTEIN | Descriptor: | HEXADECA-10,12-DIEN-1-OL, PHEROMONE-BINDING PROTEIN | Authors: | Sandler, B.H, Nikonova, L, Leal, W.S, Clardy, J. | Deposit date: | 2000-01-04 | Release date: | 2001-01-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Sexual attraction in the silkworm moth: structure of the pheromone-binding-protein-bombykol complex. Chem.Biol., 7, 2000
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1X7B
| CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH ERB-041 | Descriptor: | 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | Deposit date: | 2004-08-13 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Design of Estrogen Receptor-Beta Selective Ligands J.Am.Chem.Soc., 126, 2004
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7WA9
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7WHT
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7W5E
| Oxidase ChaP D49L mutant | Descriptor: | ChaP, FE (III) ION | Authors: | Wang, Y, Zheng, W, Meng, Z, Jin, Y, Zhu, J, Tan, R. | Deposit date: | 2021-11-30 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Alteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution. Angew.Chem.Int.Ed.Engl., 61, 2022
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7TNY
| Cryo-EM structure of RIG-I in complex with p2dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p2dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TQN
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7TQQ
| Structure of human TREX1-DNA complex | Descriptor: | DNA (5'-D(P*TP*TP*GP*GP*CP*CP*GP*GP*CP*CP*AP*TP*C)-3'), Three-prime repair exonuclease 1 | Authors: | Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. | Deposit date: | 2022-01-26 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13, 2022
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7TNX
| Cryo-EM structure of RIG-I in complex with p3dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3dsRNAa, ... | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TQP
| Structure of human TREX1 | Descriptor: | SULFATE ION, Three-prime repair exonuclease 1 | Authors: | Zhou, W, Richmond-Buccola, D, Kranzusch, P.J. | Deposit date: | 2022-01-26 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of human TREX1 DNA degradation and autoimmune disease. Nat Commun, 13, 2022
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7TQO
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7TO2
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7TO1
| Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+ATP) | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30 | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TO0
| Cryo-EM structure of RIG-I in complex with OHdsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7TNZ
| Cryo-EM structure of RIG-I in complex with p1dsRNA | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA | Authors: | Wang, W, Pyle, A.M. | Deposit date: | 2022-01-22 | Release date: | 2022-11-02 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82, 2022
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7U34
| The structure of phosphoglucose isomerase from Aspergillus fumigatus | Descriptor: | CHLORIDE ION, CITRATE ANION, GLYCEROL, ... | Authors: | Yan, K, Kowalski, B, Fang, W, van Aalten, D. | Deposit date: | 2022-02-25 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis. Mbio, 13, 2022
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7WL4
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor SLP-50 | Descriptor: | Bromodomain-containing protein 4, ~{N}-[2-ethyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]-2,4-bis(fluoranyl)benzenesulfonamide | Authors: | Zhang, C, Wang, C, Li, W, Zhang, Y, Xu, Y, Sun, L. | Deposit date: | 2022-01-12 | Release date: | 2022-08-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors. Bioorg.Chem., 127, 2022
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1F45
| HUMAN INTERLEUKIN-12 | Descriptor: | INTERLEUKIN-12 ALPHA CHAIN, INTERLEUKIN-12 BETA CHAIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yoon, C, Johnston, S.C, Tang, J, Tobin, J.F, Somers, W.S. | Deposit date: | 2000-06-07 | Release date: | 2001-06-20 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12. EMBO J., 19, 2000
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7W6V
| Crystal structure of a dicobalt-substituted small laccase at 2.47 angstrom | Descriptor: | COBALT (II) ION, Putative copper oxidase | Authors: | Yang, X, Wu, F, Wu, W, Chen, X, Fan, S, Yu, P, Mao, L. | Deposit date: | 2021-12-02 | Release date: | 2022-11-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | A versatile artificial metalloenzyme scaffold enabling direct bioelectrocatalysis in solution. Sci Adv, 8, 2022
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7WMV
| Structure of human SGLT1-MAP17 complex bound with LX2761 | Descriptor: | N-[2-(dimethylamino)ethyl]-2-methyl-2-[4-[4-[[2-methyl-5-[(2S,3R,4R,5S,6R)-6-methylsulfanyl-3,4,5-tris(oxidanyl)oxan-2-yl]phenyl]methyl]phenyl]butanoylamino]propanamide, PDZK1-interacting protein 1, Sodium/glucose cotransporter 1 | Authors: | Chen, L, Niu, Y, Cui, W. | Deposit date: | 2022-01-17 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural mechanism of SGLT1 inhibitors. Nat Commun, 13, 2022
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7W1I
| Crystal structure of carboxylesterase mutant from Thermobifida fusca with C8X and C9C | Descriptor: | 4-(2-hydroxyethyloxycarbonyl)benzoic acid, Carboxylesterase, bis(2-hydroxyethyl) benzene-1,4-dicarboxylate | Authors: | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | Deposit date: | 2021-11-19 | Release date: | 2022-11-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
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7W1K
| Crystal structure of carboxylesterase from Thermobifida fusca | Descriptor: | Carboxylesterase | Authors: | Han, X, Gerlis, H, Li, Z, Gao, J, Wei, R, Liu, W. | Deposit date: | 2021-11-19 | Release date: | 2022-11-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization Acs Catalysis, 12, 2022
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7WN7
| Crystal structure of HearNPV P26 | Descriptor: | CHLORIDE ION, SULFATE ION, p26 | Authors: | Kuang, W, Hu, Z, Gong, P. | Deposit date: | 2022-01-17 | Release date: | 2022-11-23 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Dual roles and evolutionary implications of P26/poxin in antagonizing intracellular cGAS-STING and extracellular melanization immunity. Nat Commun, 13, 2022
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7W1Q
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