5MPD
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![BU of 5mpd by Molmil](/molmil-images/mine/5mpd) | 26S proteasome in presence of ATP (s1) | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN10, ... | 著者 | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | 登録日 | 2016-12-16 | 公開日 | 2017-03-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1MCV
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![BU of 1mcv by Molmil](/molmil-images/mine/1mcv) | Crystal Structure Analysis of a Hybrid Squash Inhibitor in Complex with Porcine Pancreatic Elastase | 分子名称: | CALCIUM ION, Elastase 1, HEI-TOE I, ... | 著者 | Ay, J, Hilpert, K, Krauss, N, Schneider-Mergener, J, Hoehne, W. | 登録日 | 2002-08-06 | 公開日 | 2003-02-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
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5MDN
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![BU of 5mdn by Molmil](/molmil-images/mine/5mdn) | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis | 分子名称: | DNA polymerase, MAGNESIUM ION | 著者 | Guo, J, Zhang, W, Coker, A.R, Wood, S.P, Cooper, J.B, Rashid, N, Akhtar, M. | 登録日 | 2016-11-12 | 公開日 | 2016-12-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis. Acta Crystallogr D Struct Biol, 73, 2017
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5MFZ
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![BU of 5mfz by Molmil](/molmil-images/mine/5mfz) | Human Sirt6 in complex with small molecule UBCS40 | 分子名称: | 1,2-ETHANEDIOL, 1-pyrrolo[1,2-a]quinoxalin-4-ylnaphthalen-2-ol, NAD-dependent protein deacetylase sirtuin-6, ... | 著者 | Steegborn, C, You, W, Kambach, C. | 登録日 | 2016-11-19 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules. Angew. Chem. Int. Ed. Engl., 56, 2017
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5YTK
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![BU of 5ytk by Molmil](/molmil-images/mine/5ytk) | Crystal structure of SIRT3 bound to a leucylated AceCS2 | 分子名称: | AceCS2-KLeu, LEUCINE, LYSINE, ... | 著者 | Li, J, Gong, W, Xu, Y. | 登録日 | 2017-11-18 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations Cell Metab., 27, 2018
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5MPB
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![BU of 5mpb by Molmil](/molmil-images/mine/5mpb) | 26S proteasome in presence of AMP-PNP (s3) | 分子名称: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | 著者 | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | 登録日 | 2016-12-16 | 公開日 | 2017-03-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MTP
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![BU of 5mtp by Molmil](/molmil-images/mine/5mtp) | Crystal structure of M. tuberculosis InhA inhibited by PT514 | 分子名称: | 2-(2-methylphenoxy)-5-[(4-phenyl-1H-1,2,3-triazol-1-yl)methyl]phenol, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | 著者 | Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. | 登録日 | 2017-01-10 | 公開日 | 2017-02-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. J. Am. Chem. Soc., 139, 2017
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5M1M
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6O5N
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![BU of 6o5n by Molmil](/molmil-images/mine/6o5n) | Tubulin-RB3_SLD-TTL in complex with compound 10ab | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kumar, G, Wang, Y, Li, W, White, S.W. | 登録日 | 2019-03-04 | 公開日 | 2019-07-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin. J.Med.Chem., 62, 2019
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5OA6
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![BU of 5oa6 by Molmil](/molmil-images/mine/5oa6) | Crystal structure of ScGas2 in complex with compound 12 | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-3,5-bis(oxidanyl)-6-[4-(3-quinolin-1-ium-1-ylpropyl)-1,2,3-triazol-1-yl]oxan-4-yl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-oxane-3,4,5-triol, 1,2-ETHANEDIOL, 1,3-beta-glucanosyltransferase GAS2, ... | 著者 | Delso, I, Valero-Gonzalez, J, Gomollon-Bel, F, Castro-Lopez, J, Fang, W, Navratilova, I, Van Aalten, D, Tejero, T, Merino, P, Hurtado-Guerrero, R. | 登録日 | 2017-06-21 | 公開日 | 2018-05-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Inhibitors against Fungal Cell Wall Remodeling Enzymes. ChemMedChem, 13, 2018
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1ZD0
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![BU of 1zd0 by Molmil](/molmil-images/mine/1zd0) | Crystal structure of Pfu-542154 conserved hypothetical protein | 分子名称: | MAGNESIUM ION, METHANOL, UNKNOWN ATOM OR ION, ... | 著者 | Habel, J.E, Liu, Z.J, Horanyi, P.S, Florence, Q.J.T, Tempel, W, Zhou, W, Chen, L, Lee, D, Nguyen, J, Chang, S.H, Bereton, P, Izumi, M, Jenny Jr, F.E, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2005-04-13 | 公開日 | 2005-05-17 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Pfu-542154 conserved hypothetical protein To be Published
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5O30
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5O4W
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![BU of 5o4w by Molmil](/molmil-images/mine/5o4w) | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal | 分子名称: | Lysozyme C | 著者 | Clabbers, M.T.B, van Genderen, E, Wan, W, Wiegers, E.L, Gruene, T, Abrahams, J.P. | 登録日 | 2017-05-31 | 公開日 | 2017-08-23 | 最終更新日 | 2024-01-17 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.11 Å) | 主引用文献 | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal. Acta Crystallogr D Struct Biol, 73, 2017
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6DRK
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![BU of 6drk by Molmil](/molmil-images/mine/6drk) | Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, Apo state | 分子名称: | Transient receptor potential cation channel, subfamily M, member 2 | 著者 | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | 登録日 | 2018-06-12 | 公開日 | 2018-09-19 | 最終更新日 | 2018-10-10 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
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5NSD
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![BU of 5nsd by Molmil](/molmil-images/mine/5nsd) | Co-crystal structure of NAMPT dimer with KPT-9274 | 分子名称: | (~{E})-3-(6-azanylpyridin-3-yl)-~{N}-[[5-[4-[4,4-bis(fluoranyl)piperidin-1-yl]carbonylphenyl]-7-(4-fluorophenyl)-1-benzofuran-2-yl]methyl]prop-2-enamide, GLYCEROL, Nicotinamide phosphoribosyltransferase, ... | 著者 | Neggers, J.E, Kwanten, B, Dierckx, T, Noguchi, H, Voet, A, Vercruysse, T, Baloglu, E, Senapedis, W, Jacquemyn, M, Daelemans, D. | 登録日 | 2017-04-26 | 公開日 | 2018-02-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.046 Å) | 主引用文献 | Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes. Nat Commun, 9, 2018
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5NUS
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![BU of 5nus by Molmil](/molmil-images/mine/5nus) | Structure of a minimal complex between p44 and p34 from Chaetomium thermophilum | 分子名称: | ZINC ION, p34, p44 | 著者 | Koelmel, W, Schoenwetter, E, Kuper, J, Schmitt, D.R, Kisker, C. | 登録日 | 2017-05-02 | 公開日 | 2017-10-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The intricate network between the p34 and p44 subunits is central to the activity of the transcription/DNA repair factor TFIIH. Nucleic Acids Res., 45, 2017
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3DBQ
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![BU of 3dbq by Molmil](/molmil-images/mine/3dbq) | Crystal structure of TTK kinase domain | 分子名称: | Dual specificity protein kinase TTK | 著者 | Wang, W, Yang, Y.T, Gao, Y.F, Zhu, S.C, Wang, F, Old, W, Xu, Q.B, Resing, K, Ahn, N, Lei, M, Liu, X.D. | 登録日 | 2008-06-02 | 公開日 | 2009-02-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Mechanistic Insights into Mps1 Kinase Activation J.CELL.MOL.MED., 13, 2008
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5N01
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![BU of 5n01 by Molmil](/molmil-images/mine/5n01) | Crystal structure of the decarboxylase AibA/AibB C56N variant | 分子名称: | ACETATE ION, GLYCEROL, Glutaconate CoA-transferase family, ... | 著者 | Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2017-02-02 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angew. Chem. Int. Ed. Engl., 56, 2017
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5MZX
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![BU of 5mzx by Molmil](/molmil-images/mine/5mzx) | Crystal structure of the decarboxylase AibA/AibB in complex with 4'-diphospho pantetheine | 分子名称: | 4'-diphospho pantetheine, ACETATE ION, GLYCEROL, ... | 著者 | Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. | 登録日 | 2017-02-02 | 公開日 | 2017-05-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angew. Chem. Int. Ed. Engl., 56, 2017
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1CXR
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5N7C
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![BU of 5n7c by Molmil](/molmil-images/mine/5n7c) | Human TTR altered conformation from soaking in CuCl2. | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, COPPER (II) ION, ... | 著者 | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | 登録日 | 2017-02-20 | 公開日 | 2018-03-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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5ZCC
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5N88
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![BU of 5n88 by Molmil](/molmil-images/mine/5n88) | Crystal structure of antibody bound to viral protein | 分子名称: | PC4 and SFRS1-interacting protein, VH59 antibody | 著者 | Bao, L, Hannon, C, Cruz-Migoni, A, Ptchelkine, D, Sun, M.-y, Derveni, M, Bunjobpol, W, Chambers, J.S, Simmons, A, Phillips, S.E.V, Rabbitts, T.H. | 登録日 | 2017-02-23 | 公開日 | 2017-12-20 | 最終更新日 | 2019-10-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein. Sci Rep, 7, 2017
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5N62
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![BU of 5n62 by Molmil](/molmil-images/mine/5n62) | Human TTR crystals soaked in manganese chloride. | 分子名称: | MANGANESE (II) ION, Transthyretin | 著者 | Ciccone, L, Savko, M, Shepard, W, Stura, E.A. | 登録日 | 2017-02-14 | 公開日 | 2018-03-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8, 2018
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6DRJ
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![BU of 6drj by Molmil](/molmil-images/mine/6drj) | Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel, ... | 著者 | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | 登録日 | 2018-06-12 | 公開日 | 2018-09-19 | 最終更新日 | 2018-10-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
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