5N62

Human TTR crystals soaked in manganese chloride.

Summary for 5N62

• Entry DOI: 10.2210/pdb5n62/pdb
• Related: 5K1J 5K1N 5N5Q
• Descriptor: Transthyretin, MANGANESE (II) ION (3 entities in total)
• Functional Keywords: manganese complex, metal binding, alzheimer beta-amyloid scavenging, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 25774.67

Authors

Ciccone, L.,Savko, M.,Shepard, W.,Stura, E.A. (deposition date: 2017-02-14, release date: 2018-03-07, Last modification date: 2024-01-17)

• Primary citation: Ciccone, L.,Fruchart-Gaillard, C.,Mourier, G.,Savko, M.,Nencetti, S.,Orlandini, E.,Servent, D.,Stura, E.A.,Shepard, W.; Copper mediated amyloid-beta binding to Transthyretin.; Sci Rep, 8:13744-13744, 2018; PubMed: 30213975; DOI: 10.1038/s41598-018-31808-5

Experimental method

X-RAY DIFFRACTION (1.8 Å)