26S proteasome in presence of AMP-PNP (s3)

This is a large structure.

Summary for 5MPB

EMDB information3536
DescriptorProteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... (36 entities in total)
Functional Keywordsmacromolecular complex, 26s proteasome, protease, hydrolase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular locationCytoplasm  P21243 P23639 P23638 P40303 P32379 P40302 P21242 P38624 P25043 P25451 P22141 P30656 P23724 P30657 P33299 P40327 P33298 P33297 Q01939 O13563
Total number of polymer chains47
Total molecular weight1695763.86
Wehmer, M.,Rudack, T.,Beck, F.,Aufderheide, A.,Pfeifer, G.,Plitzko, J.M.,Foerster, F.,Schulten, K.,Baumeister, W.,Sakata, E. (deposition date: 2016-12-16, release date: 2017-03-08, Last modification date: 2017-08-02)
Primary citation
Wehmer, M.,Rudack, T.,Beck, F.,Aufderheide, A.,Pfeifer, G.,Plitzko, J.M.,Forster, F.,Schulten, K.,Baumeister, W.,Sakata, E.
Structural insights into the functional cycle of the ATPase module of the 26S proteasome.
Proc. Natl. Acad. Sci. U.S.A., 114:1305-1310, 2017
PubMed: 28115689 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1621129114
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers31.4%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 5mpb
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Molmil generated image of 5mpb
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Molmil generated image of 5mpb
rotated about y axis by 90°
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