5N7C
Human TTR altered conformation from soaking in CuCl2.
Summary for 5N7C
| Entry DOI | 10.2210/pdb5n7c/pdb |
| Related | 5K1J 5K1N 5N5Q 5N62 |
| Descriptor | Transthyretin, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
| Functional Keywords | copper ttr complex, metal binding, alzheimer beta-amyloid scavenging, transport protein |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 26340.89 |
| Authors | Ciccone, L.,Savko, M.,Shepard, W.,Stura, E.A. (deposition date: 2017-02-20, release date: 2018-03-14, Last modification date: 2024-01-17) |
| Primary citation | Ciccone, L.,Fruchart-Gaillard, C.,Mourier, G.,Savko, M.,Nencetti, S.,Orlandini, E.,Servent, D.,Stura, E.A.,Shepard, W. Copper mediated amyloid-beta binding to Transthyretin. Sci Rep, 8:13744-13744, 2018 Cited by PubMed: 30213975DOI: 10.1038/s41598-018-31808-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
Download full validation report
