6K0Q
 
 | | Catalytic domain of GH87 alpha-1,3-glucanase D1068A in complex with nigerose | | 分子名称: | ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ... | | 著者 | Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T. | | 登録日 | 2019-05-07 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.564 Å) | | 主引用文献 | Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
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6K3Z
 | | Crystal structure of dCas9 in complex with sgRNA and DNA (TGA PAM) | | 分子名称: | CRISPR-associated endonuclease Cas9, DNA (28-MER), DNA (5'-D(*AP*AP*AP*TP*GP*AP*TP*AP*TP*TP*G)-3'), ... | | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | 登録日 | 2019-05-22 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
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6K4P
 | | Crystal structure of xCas9 in complex with sgRNA and DNA (TGG PAM) | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (28-MER), PHOSPHATE ION, ... | | 著者 | Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q. | | 登録日 | 2019-05-25 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019
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6I61
 | | Crystal structure of human ERRg LBD in complex with bisphenol-B | | 分子名称: | 1,2-ETHANEDIOL, Estrogen-related receptor gamma, GLYCEROL, ... | | 著者 | Delfosse, V, Blanc, P, Bourguet, W. | | 登録日 | 2018-11-15 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Insights into the activation mechanism of human estrogen-related receptor gamma by environmental endocrine disruptors.
Cell.Mol.Life Sci., 76, 2019
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6INZ
 | | Crystal structure of solute-binding protein complexed with unsaturated hyaluronan disaccharide | | 分子名称: | 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Extracellular solute-binding protein family 1, ... | | 著者 | Oiki, S, Mikami, B, Murata, K, Hashimoto, W. | | 登録日 | 2018-10-29 | | 公開日 | 2019-09-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.289 Å) | | 主引用文献 | Substrate recognition by bacterial solute-binding protein is responsible for import of extracellular hyaluronan and chondroitin sulfate from the animal host.
Biosci.Biotechnol.Biochem., 83, 2019
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6IRB
 | | C-terminal coiled coil domain of Drosophila phospholipase C beta NORPA, selenomethionine | | 分子名称: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase | | 著者 | Ye, F, Li, J, Huang, Y, Liu, W, Zhang, M. | | 登録日 | 2018-11-12 | | 公開日 | 2019-01-02 | | 最終更新日 | 2020-10-28 | | 実験手法 | X-RAY DIFFRACTION (2.661 Å) | | 主引用文献 | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
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6IS6
 | | Crystal structure of Thermoplasmatales archaeon heliorhodopsin | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, RETINAL, heliorhodopsin | | 著者 | Shihoya, W, Yamashita, K, Nureki, O. | | 登録日 | 2018-11-15 | | 公開日 | 2019-09-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of heliorhodopsin.
Nature, 574, 2019
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6IBW
 | | Crh5 transglycosylase in complex with NAG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Probable glycosidase crf1 | | 著者 | Fang, W, Bartual, S.G, van Aalten, D.M.F. | | 登録日 | 2018-12-01 | | 公開日 | 2019-02-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mechanisms of redundancy and specificity of the Aspergillus fumigatus Crh transglycosylases.
Nat Commun, 10, 2019
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6IF8
 | | Aeromonas hydrophila MtaN-2 complexed with adenine | | 分子名称: | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | | 著者 | Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Aeromonas hydrophila MtaN-2 complexed with adenine
To Be Published
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5WBV
 | | Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor | | 分子名称: | 2-chloro-5-(4-methyl-6-oxo-3-phenylpyrano[2,3-c]pyrazol-1(6H)-yl)benzoic acid, Histone-lysine N-methyltransferase KMT5B, S-ADENOSYLMETHIONINE, ... | | 著者 | Halabelian, L, Tempel, W, Brown, P.J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-06-29 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor
To be published
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7CKF
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6HYL
 | | Structure of PCM1 LIR motif bound to GABARAP | | 分子名称: | Pericentriolar material 1 protein,Gamma-aminobutyric acid receptor-associated protein | | 著者 | Mouilleron, S, Wirth, M, Zhang, W, O'Reilly, N, Tooze, S, Johansen, T, Razi, M, Nyoni, L, Joshi, D. | | 登録日 | 2018-10-22 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.559 Å) | | 主引用文献 | Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.
Nat Commun, 10, 2019
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5WHQ
 | | Crystal structure of the catalase-peroxidase from Neurospora crassa at 2.9 A | | 分子名称: | Catalase-peroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Diaz-Vilchis, A, Vega-Garcia, V, Rudino-Pinera, E, Hansberg, W. | | 登録日 | 2017-07-18 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure, kinetics, molecular and redox properties of a cytosolic and developmentally regulated fungal catalase-peroxidase.
Arch. Biochem. Biophys., 640, 2018
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6HLU
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5W96
 | | Solution structure of phage derived peptide inhibitor of frizzled 7 receptor | | 分子名称: | Fz7 binding peptide | | 著者 | Nile, A.H, de Sousa e Melo, F, Mukund, S, Piskol, R, Hansen, S, Zhou, L, Zhang, Y, Fu, Y, Gogol, E.B, Komuves, L.G, Modrusan, Z, Angers, S, Franke, Y, Koth, C, Fairbrother, W.J, Wang, W, de Sauvage, F.J, Hannoush, R.N. | | 登録日 | 2017-06-22 | | 公開日 | 2018-04-18 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nat. Chem. Biol., 14, 2018
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5WPY
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6HOL
 | | Structure of ATG14 LIR motif bound to GABARAPL1 | | 分子名称: | Beclin 1-associated autophagy-related key regulator, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein-like 1, ... | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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6HOY
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6HEC
 | | PAN-proteasome in state 4 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Majumder, P, Rudack, T, Beck, F, Baumeister, W. | | 登録日 | 2018-08-20 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.95 Å) | | 主引用文献 | Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6HOJ
 | | Structure of Beclin1 LIR motif bound to GABARAP | | 分子名称: | 1,2-ETHANEDIOL, Beclin-1,Gamma-aminobutyric acid receptor-associated protein, SULFATE ION | | 著者 | Mouilleron, S, Birgisdottir, A.B, Bhujbal, Z, Wirth, M, Sjottem, E, Evjen, G, Zhang, W, Lee, R, O'Reilly, N, Tooze, S, Lamark, T, Johansen, T. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.
Autophagy, 15, 2019
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5W0S
 | | GroEL using cryoEM | | 分子名称: | 60 kDa chaperonin | | 著者 | Roh, S.H, Chiu, W. | | 登録日 | 2017-05-31 | | 公開日 | 2017-08-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6HRF
 | | Straight filament from sporadic Alzheimer's disease brain | | 分子名称: | Microtubule-associated protein tau | | 著者 | Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M. | | 登録日 | 2018-09-26 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
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5W5G
 | | Structure of Human Sts-1 histidine phosphatase domain | | 分子名称: | Ubiquitin-associated and SH3 domain-containing protein B | | 著者 | Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B. | | 登録日 | 2017-06-15 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2.
Biochemistry, 56, 2017
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6JYY
 | | Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia | | 分子名称: | Hydroxyethylthiazole kinase | | 著者 | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | | 登録日 | 2019-04-29 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 518, 2019
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6K6I
 | | The crystal structure of light-driven cyanobacterial chloride importer from Mastigocladopsis repens | | 分子名称: | CHLORIDE ION, Cyanobacterial chloride importer, OLEIC ACID, ... | | 著者 | Yun, J.H, Park, J.H, Jin, Z, Ohki, M, Wang, Y, Lupala, C.S, Kim, M, Liu, H, Park, S.Y, Lee, W. | | 登録日 | 2019-06-03 | | 公開日 | 2020-06-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The crystal structure of light-driven cyanobacterial chloride importer from Mastigocladopsis repens
To Be Published
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