5WBV

Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor

Summary for 5WBV

• Entry DOI: 10.2210/pdb5wbv/pdb
• Descriptor: Histone-lysine N-methyltransferase KMT5B, ZINC ION, S-ADENOSYLMETHIONINE, ... (6 entities in total)
• Functional Keywords: set domain, methyltransferase, protein-inhibitor complex, sgc, structural genomics, structural genomics consortium, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q4FZB7
• Total number of polymer chains: 2
• Total formula weight: 64888.77

Authors

Halabelian, L.,Tempel, W.,Brown, P.J.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-29, release date: 2017-07-19, Last modification date: 2023-10-04)

• Primary citation: Halabelian, L.,Tempel, W.,Brown, P.J.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Structural Genomics Consortium (SGC); Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor; To be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)