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5WBV

Crystal Structure of the SET Domain of Human SUV420H1 In Complex With Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histone-lysine N-methyltransferase KMT5Bpolymer27331599.82UniProt (Q4FZB7)
Pfam (PF00856)
Homo sapiens (Human)Lysine N-methyltransferase 5B,Lysine-specific methyltransferase 5B,Suppressor of variegation 4-20 homolog 1,Suv4-20h1
2C, L
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, M
(A, B)
S-ADENOSYLMETHIONINEnon-polymer398.42Chemie (SAM)
4E, N
(A, B)
2-chloro-5-(4-methyl-6-oxo-3-phenylpyrano[2,3-c]pyrazol-1(6H)-yl)benzoic acidnon-polymer380.82Chemie (9ZY)
5F, G, H, I, J...
(A, B)
UNKNOWN ATOM OR IONnon-polymer12Chemie (UNX)
6U, V
(A, B)
waterwater18.031Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63199.5
Non-Polymers*Number of molecules18
Total formula weight1689.3
All*Total formula weight64888.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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