2OD1
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![BU of 2od1 by Molmil](/molmil-images/mine/2od1) | Solution structure of the MYND domain from human AML1-ETO | 分子名称: | Protein CBFA2T1, ZINC ION | 著者 | Liu, Y.Z, Chen, W, Gaudet, J, Cheney, M.D, Roudaia, L, Cierpicki, T, Klet, R.C, Hartman, K, Laue, T.M, Speck, N.A, Bushweller, J.H. | 登録日 | 2006-12-21 | 公開日 | 2007-06-19 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity. Cancer Cell, 11, 2007
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1ZVA
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![BU of 1zva by Molmil](/molmil-images/mine/1zva) | A structure-based mechanism of SARS virus membrane fusion | 分子名称: | E2 glycoprotein | 著者 | Deng, Y, Liu, J, Zheng, Q, Yong, W, Dai, J, Lu, M. | 登録日 | 2005-06-01 | 公開日 | 2006-05-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures and Polymorphic Interactions of Two Heptad-Repeat Regions of the SARS Virus S2 Protein. Structure, 14, 2006
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2NSW
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2OIL
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![BU of 2oil by Molmil](/molmil-images/mine/2oil) | Crystal structure of human RAB25 in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-25, ... | 著者 | Zhu, H, Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2007-01-11 | 公開日 | 2007-01-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of human RAB25 in complex with GDP To be Published
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4N70
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![BU of 4n70 by Molmil](/molmil-images/mine/4n70) | Pim1 Complexed with a pyridylcarboxamide | 分子名称: | N-{4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl}-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide, Serine/threonine-protein kinase pim-1 | 著者 | Bellamacina, C.R, Le, V, Shu, W, Burger, M.T, Bussiere, D. | 登録日 | 2013-10-14 | 公開日 | 2013-11-06 | 最終更新日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors. ACS Med Chem Lett, 4, 2013
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3TA1
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![BU of 3ta1 by Molmil](/molmil-images/mine/3ta1) | A. fulgidus GlnK3, MgADP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nitrogen regulatory protein P-II (GlnB-3) | 著者 | Maier, S, Schleberger, P, Lue, W, Wacker, T, Pflueger, T, Litz, C, Andrade, S.L.A. | 登録日 | 2011-08-03 | 公開日 | 2011-10-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. Plos One, 6, 2011
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3MYW
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![BU of 3myw by Molmil](/molmil-images/mine/3myw) | The Bowman-Birk type inhibitor from mung bean in ternary complex with porcine trypsin | 分子名称: | Bowman-Birk type trypsin inhibitor, CALCIUM ION, Trypsin | 著者 | Engh, R.A, Bode, W, Huber, R, Lin, G, Chi, C. | 登録日 | 2010-05-11 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The 0.25-nm X-ray structure of the Bowman-Birk-type inhibitor from mung bean in ternary complex with porcine trypsin. Eur.J.Biochem., 212, 1993
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1ZR4
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![BU of 1zr4 by Molmil](/molmil-images/mine/1zr4) | Structure of a Synaptic gamma-delta Resolvase Tetramer Covalently linked to two Cleaved DNAs | 分子名称: | AAA, TCAGTGTCCGATAATTTAT, TTATCGGACACTG, ... | 著者 | Li, W, Kamtekar, S, Xiong, Y, Sarkis, G.J, Grindley, N.D, Steitz, T.A. | 登録日 | 2005-05-19 | 公開日 | 2005-08-30 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structure of a synaptic gamma delta resolvase tetramer covalently linked to two cleaved DNAs. Science, 309, 2005
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2NS8
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![BU of 2ns8 by Molmil](/molmil-images/mine/2ns8) | How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor | 分子名称: | 16 residue peptide Tip (Transcription inducing peptide), Tetracycline repressor protein | 著者 | Luckner, S.R, Klotzsche, M, Berens, C, Hillen, W, Muller, Y.A. | 登録日 | 2006-11-03 | 公開日 | 2007-07-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor J.Mol.Biol., 368, 2007
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6NQ0
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![BU of 6nq0 by Molmil](/molmil-images/mine/6nq0) | Cryo-EM structure of human TPC2 channel in the ligand-bound open state | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Two pore calcium channel protein 2 | 著者 | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | 登録日 | 2019-01-18 | 公開日 | 2019-03-27 | 最終更新日 | 2019-11-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural mechanisms of phospholipid activation of the human TPC2 channel. Elife, 8, 2019
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6NQU
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![BU of 6nqu by Molmil](/molmil-images/mine/6nqu) | Human LSD1 in complex with GSK2879552 | 分子名称: | Lysine-specific histone demethylase 1A, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[(9~{S},11~{R})-15,16-dimethyl-11-oxidanyl-5,7-bis(oxidanylidene)-9-phenyl-2,4,6,12-tetrazabicyclo[11.4.0]heptadeca-1(17),13,15-trien-2-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate | 著者 | Tan, A.H.Y, Tu, W, McCuaig, R, Donovan, T, Tsimbalyuk, S, Forwood, J.K, Rao, S. | 登録日 | 2019-01-21 | 公開日 | 2019-02-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer. Front Immunol, 10, 2019
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4N9K
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![BU of 4n9k by Molmil](/molmil-images/mine/4n9k) | crystal structure of beta-lactamse PenP_E166S in complex with cephaloridine | 分子名称: | 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase | 著者 | Pan, X, Wong, W, Zhao, Y. | 登録日 | 2013-10-21 | 公開日 | 2014-09-10 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Perturbing the General Base Residue Glu166 in the Active Site of Class A beta-Lactamase Leads to Enhanced Carbapenem Binding and Acylation Biochemistry, 53, 2014
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6NRC
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![BU of 6nrc by Molmil](/molmil-images/mine/6nrc) | hTRiC-hPFD Class3 | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | 著者 | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | 登録日 | 2019-01-23 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
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3MXR
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![BU of 3mxr by Molmil](/molmil-images/mine/3mxr) | SHV-1 beta-lactamase complex with compound 1 | 分子名称: | ({[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-4-(4-hydroxyphenyl)butanoyl]amino}methyl)boronic acid, Beta-lactamase SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | 著者 | Ke, W, van den Akker, F. | 登録日 | 2010-05-07 | 公開日 | 2010-11-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Novel Insights into the Mode of Inhibition of Class A SHV-1 {beta}-Lactamases Revealed by Boronic Acid Transition State Inhibitors. Antimicrob.Agents Chemother., 55, 2011
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2NU4
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![BU of 2nu4 by Molmil](/molmil-images/mine/2nu4) | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I | 分子名称: | Ovomucoid, Streptogrisin B, Proteinase B | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | 登録日 | 2006-11-08 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I To be Published
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3MX5
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![BU of 3mx5 by Molmil](/molmil-images/mine/3mx5) | Lassa fever virus nucleoprotein complexed with UTP | 分子名称: | Nucleoprotein, URIDINE 5'-TRIPHOSPHATE, ZINC ION | 著者 | Qi, X, Lan, S, Wang, W, Schelde, L.M, Dong, H, Wallat, G, Liang, Y, Ly, H, Dong, C, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2010-05-06 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | 主引用文献 | Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature, 468, 2010
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6NR9
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![BU of 6nr9 by Molmil](/molmil-images/mine/6nr9) | hTRiC-hPFD Class5 | 分子名称: | Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... | 著者 | Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. | 登録日 | 2019-01-23 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | 主引用文献 | The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
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1Y3N
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![BU of 1y3n by Molmil](/molmil-images/mine/1y3n) | Structure of AlgQ1, alginate-binding protein, complexed with an alginate disaccharide | 分子名称: | AlgQ1, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid | 著者 | Momma, K, Mishima, Y, Hashimoto, W, Mikami, B, Murata, K. | 登録日 | 2004-11-26 | 公開日 | 2005-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Direct Evidence for Sphingomonas sp. A1 Periplasmic Proteins as Macromolecule-Binding Proteins Associated with the ABC Transporter: Molecular Insights into Alginate Transport in the Periplasm(,) Biochemistry, 44, 2005
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1Y74
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8XZF
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![BU of 8xzf by Molmil](/molmil-images/mine/8xzf) | Cryo-EM structure of the WN561-bound human APLNR-Gi complex | 分子名称: | Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, W, Ji, S, Zhang, Y. | 登録日 | 2024-01-21 | 公開日 | 2024-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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3C3H
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![BU of 3c3h by Molmil](/molmil-images/mine/3c3h) | alpha/beta-Peptide helix bundles: A GCN4-pLI analogue with an (alpha-alpha-beta) backbone and cyclic beta residues | 分子名称: | alpha/beta-peptide based on the GCN4-pLI side chain sequence, with an (alpha-alpha-beta) backbone and cyclic beta-residues at positions 1, 4, ... | 著者 | Horne, W.S, Price, J.L, Gellman, S.H. | 登録日 | 2008-01-28 | 公開日 | 2008-06-17 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2O0Y
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![BU of 2o0y by Molmil](/molmil-images/mine/2o0y) | Crystal structure of putative transcriptional regulator RHA1_ro06953 (IclR-family) from Rhodococcus sp. | 分子名称: | Transcriptional regulator | 著者 | Chruszcz, M, Wang, S, Skarina, T, Onopriyenko, O, Cymborowski, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-11-28 | 公開日 | 2006-12-26 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Putative Transcriptional Regul 2 Rha1_Ro06953(Iclr-Family) from Rhodococcus Sp. To be Published
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2NZV
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![BU of 2nzv by Molmil](/molmil-images/mine/2nzv) | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Catabolite control protein, Phosphocarrier protein HPr, ... | 著者 | Schumacher, M.A, Hillen, W, Brennan, R.G. | 登録日 | 2006-11-25 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate. J.Mol.Biol., 368, 2007
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2O20
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![BU of 2o20 by Molmil](/molmil-images/mine/2o20) | Crystal structure of transcription regulator CcpA of Lactococcus lactis | 分子名称: | CHLORIDE ION, Catabolite control protein A, SULFATE ION | 著者 | Loll, B, Kowalczyk, M, Alings, C, Chieduch, A, Bardowski, J, Saenger, W, Biesiadka, J. | 登録日 | 2006-11-29 | 公開日 | 2007-03-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the transcription regulator CcpA from Lactococcus lactis Acta Crystallogr.,Sect.D, 63, 2007
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4PMJ
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![BU of 4pmj by Molmil](/molmil-images/mine/4pmj) | Crystal structure of a putative oxidoreductase from Sinorhizobium meliloti 1021 in complex with NADP | 分子名称: | GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative oxidoreductase | 著者 | Gasiorowska, O.A, Shabalin, I.G, Handing, K.B, Szlachta, K, Zimmerman, M.D, Hillerich, B.S, Gizzi, A, Toro, R, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-05-21 | 公開日 | 2014-06-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a putative oxidoreductase from Sinorhizobiummeliloti 1021 in complex with NADP to be published
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