2AMM
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![BU of 2amm by Molmil](/molmil-images/mine/2amm) | Crystal structure of L122V/L132V mutant of nitrophorin 2 | Descriptor: | Nitrophorin 2, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Weichsel, A, Berry, R.E, Walker, F.A, Montfort, W.R. | Deposit date: | 2005-08-09 | Release date: | 2006-07-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures, ligand induced conformational change and heme deformation in complexes of nitrophorin 2, a nitric oxide transport protein from rhodnius prolixus To be Published
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4YM4
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![BU of 4ym4 by Molmil](/molmil-images/mine/4ym4) | Truncated Human TIFA in complex with its Thr9 phosphorylated N-terminal peptide 1-15 | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | Authors: | Weng, J.H, Wei, T.Y.W, Hsieh, Y.C, Huang, C.C.F, Wu, P.Y.G, Chen, E.S.W, Huang, K.F, Chen, C.J, Tsai, M.D. | Deposit date: | 2015-03-06 | Release date: | 2015-10-21 | Last modified: | 2015-10-28 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses. Biochemistry, 54, 2015
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4AGS
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![BU of 4ags by Molmil](/molmil-images/mine/4ags) | Leishmania TDR1 - a unique trimeric glutathione transferase | Descriptor: | 1,2-ETHANEDIOL, GLUTATHIONE, THIOL-DEPENDENT REDUCTASE 1 | Authors: | Fyfe, P.K, Westrop, G.D, Silva, A.M, Coombs, G.H, Hunter, W.N. | Deposit date: | 2012-01-31 | Release date: | 2012-07-04 | Last modified: | 2012-08-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Leishmania Tdr1 Structure, a Unique Trimeric Glutathione Transferase Capable of Deglutathionylation and Antimonial Prodrug Activation. Proc.Natl.Acad.Sci.USA, 109, 2012
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4YOM
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![BU of 4yom by Molmil](/molmil-images/mine/4yom) | Structure of SAD kinase | Descriptor: | 1,2-ETHANEDIOL, Serine/threonine-protein kinase BRSK2 | Authors: | Wu, J.X, Wang, J, Chen, L, Wang, Z.X, Wu, J.W. | Deposit date: | 2015-03-12 | Release date: | 2015-12-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structural insight into the mechanism of synergistic autoinhibition of SAD kinases Nat Commun, 6, 2015
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4YPO
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![BU of 4ypo by Molmil](/molmil-images/mine/4ypo) | |
4YQL
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![BU of 4yql by Molmil](/molmil-images/mine/4yql) | Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds | Descriptor: | 4-amino-N-[(1S,2R)-2-(4-sulfamoylphenyl)cyclopropyl]-1,2,5-oxadiazole-3-carboxamide, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Elkins, P.A, Bonnette, W.G, Madauss, K.P. | Deposit date: | 2015-03-13 | Release date: | 2016-03-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds To Be Published
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4YQQ
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2ARS
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![BU of 2ars by Molmil](/molmil-images/mine/2ars) | Crystal structure of lipoate-protein ligase A From Thermoplasma acidophilum | Descriptor: | Lipoate-protein ligase A, MAGNESIUM ION | Authors: | Kim, D.J, Kim, K.H, Lee, H.H, Lee, S.J, Ha, J.Y, Yoon, H.J, Suh, S.W. | Deposit date: | 2005-08-22 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains J.Biol.Chem., 280, 2005
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4AAR
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![BU of 4aar by Molmil](/molmil-images/mine/4aar) | ATP-triggered molecular mechanics of the chaperonin GroEL | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R. | Deposit date: | 2011-12-05 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin. Cell(Cambridge,Mass.), 149, 2012
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4BL7
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4YDG
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![BU of 4ydg by Molmil](/molmil-images/mine/4ydg) | Crystal structure of compound 10 in complex with HTLV-1 Protease | Descriptor: | HTLV-1 protease, N,N'-(3S,4S)-PYRROLIDINE-3,4-DIYLBIS(4-AMINO-N-BENZYLBENZENESULFONAMIDE), SULFATE ION | Authors: | Kuhnert, M, Blum, A, Steuber, H, Diederich, W.E. | Deposit date: | 2015-02-22 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C2-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors. J.Med.Chem., 58, 2015
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1FSP
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![BU of 1fsp by Molmil](/molmil-images/mine/1fsp) | NMR SOLUTION STRUCTURE OF BACILLUS SUBTILIS SPO0F PROTEIN, 20 STRUCTURES | Descriptor: | STAGE 0 SPORULATION PROTEIN F | Authors: | Feher, V.A, Skelton, N.J, Dahlquist, F.W, Cavanagh, J. | Deposit date: | 1997-06-05 | Release date: | 1997-12-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, Spo0F: implications for phosphorylation and molecular recognition. Biochemistry, 36, 1997
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4YEB
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![BU of 4yeb by Molmil](/molmil-images/mine/4yeb) | Structural characterization of a synaptic adhesion complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibronectin leucine rich transmembrane protein 3, ... | Authors: | Ranaivoson, F.M, Liu, Q, Martini, F, Bergami, F, von Daake, S, Li, S, Lee, D, Demeler, B, Hendrickson, W.A, Comoletti, D. | Deposit date: | 2015-02-23 | Release date: | 2015-08-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development. Structure, 23, 2015
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5MVW
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![BU of 5mvw by Molmil](/molmil-images/mine/5mvw) | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Centrosomin, ... | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-17 | Release date: | 2017-06-28 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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5MW0
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![BU of 5mw0 by Molmil](/molmil-images/mine/5mw0) | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form | Descriptor: | Centrosomin, ZINC ION | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | Deposit date: | 2017-01-17 | Release date: | 2017-06-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies. Cell, 169, 2017
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4YGW
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![BU of 4ygw by Molmil](/molmil-images/mine/4ygw) | RNase S in complex with stabilized S peptide | Descriptor: | 1-hydroxypropan-2-one, Ribonuclease A C2, S-peptide: ACE-LYS-GLU-THR-ALA-ALA-HCS-LYS-PHE-GLU-HCS-GLN-HIS-MET-ASP-SER, ... | Authors: | Assem, N, Ferreira, D, Wolan, D.W, Dawson, P.E. | Deposit date: | 2015-02-26 | Release date: | 2015-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling. Angew.Chem.Int.Ed.Engl., 54, 2015
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3OR1
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![BU of 3or1 by Molmil](/molmil-images/mine/3or1) | Crystal structure of dissimilatory sulfite reductase I (DsrI) | Descriptor: | IRON/SULFUR CLUSTER, SIROHEME, SULFITE ION, ... | Authors: | Hsieh, Y.C, Liu, M.Y, Wang, V.C.C, Chiang, Y.L, Liu, E.H, Wu, W.G, Chan, S.I, Chen, C.J. | Deposit date: | 2010-09-06 | Release date: | 2010-09-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structure insights into the enzyme catalysis from comparison of three forms of dissimilatory sulfite reductase from Desulfovibrio gigas To be Published
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4YIC
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![BU of 4yic by Molmil](/molmil-images/mine/4yic) | CRYSTAL STRUCTURE OF A TRAP TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM BORDETELLA BRONCHISEPTICA RB50 (BB0280, TARGET EFI-500035) WITH BOUND PICOLINIC ACID | Descriptor: | ACETATE ION, CALCIUM ION, IMIDAZOLE, ... | Authors: | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2015-03-01 | Release date: | 2015-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | CRYSTAL STRUCTURE OF A TRAP TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM BORDETELLA BRONCHISEPTICA RB50 (BB0280, TARGET EFI-500035) WITH BOUND PICOLINIC ACID To be published
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5MGB
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![BU of 5mgb by Molmil](/molmil-images/mine/5mgb) | Crystal Structure of Rat Peroxisomal Multifunctional enzyme Type-1 (RPMFE1) Complexed with Acetoacetyl-CoA and NAD | Descriptor: | ACETOACETYL-COENZYME A, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Kasaragod, P, Kiema, T.-R, Schmitz, W, Hiltunen, J.K, Wierenga, R.K. | Deposit date: | 2016-11-21 | Release date: | 2016-12-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural enzymology comparisons of multifunctional enzyme, type-1 (MFE1): the flexibility of its dehydrogenase part. FEBS Open Bio, 7, 2017
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6N31
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![BU of 6n31 by Molmil](/molmil-images/mine/6n31) | WD repeats of human WDR12 | Descriptor: | Ribosome biogenesis protein WDR12, UNKNOWN ATOM OR ION | Authors: | Halabelian, L, Zeng, H, Tempel, W, Li, Y, Seitova, A, Hutchinson, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2018-11-14 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | WD repeats of human WDR12 To Be Published
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1JYM
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![BU of 1jym by Molmil](/molmil-images/mine/1jym) | Crystals of Peptide Deformylase from Plasmodium falciparum with Ten Subunits per Asymmetric Unit Reveal Critical Characteristics of the Active Site for Drug Design | Descriptor: | COBALT (II) ION, Peptide Deformylase | Authors: | Kumar, A, Nguyen, K.T, Srivathsan, S, Ornstein, B, Turley, S, Hirsh, I, Pei, D, Hol, W.G.J. | Deposit date: | 2001-09-12 | Release date: | 2002-03-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design. Structure, 10, 2002
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2AMS
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![BU of 2ams by Molmil](/molmil-images/mine/2ams) | Structure of the oxidized Hipip from thermochromatium tepidum at 1.4 angstrom resolution | Descriptor: | GLYCEROL, High potential iron-sulfur protein, IRON/SULFUR CLUSTER, ... | Authors: | Hunsicker-Wang, L.M, Han, W, Stout, C.D, Noodleman, L, Fee, J.A. | Deposit date: | 2005-08-10 | Release date: | 2006-08-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Geometric factors determine, in part, the electronic state of the 4Fe-4S cluster of Hipip from thermochromtium tepidum: a geomteric, crystallographic, and theoretical study. To be Published
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5MUG
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![BU of 5mug by Molmil](/molmil-images/mine/5mug) | Self-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier | Descriptor: | (2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL, Alpha-tocopherol transfer protein, CHLORIDE ION, ... | Authors: | Stocker, A, Aeschimann, W. | Deposit date: | 2017-01-13 | Release date: | 2017-07-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Self-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an Endothelial Barrier. Sci Rep, 7, 2017
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1XT5
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![BU of 1xt5 by Molmil](/molmil-images/mine/1xt5) | Crystal Structure of VCBP3, domain 1, from Branchiostoma floridae | Descriptor: | SULFATE ION, variable region-containing chitin-binding protein 3 | Authors: | Hernandez Prada, J.A, Haire, R.N, Cannon, J.P, Allaire, M, Jakoncic, J, Stojanoff, V, Litman, G.W, Ostrov, D.A. | Deposit date: | 2004-10-21 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus. Nat.Immunol., 7, 2006
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4YDF
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![BU of 4ydf by Molmil](/molmil-images/mine/4ydf) | Crystal structure of compound 9 in complex with HTLV-1 Protease | Descriptor: | HTLV-1 Protease, N-benzyl-N-[(3S,4S)-4-{benzyl[(4-nitrophenyl)sulfonyl]amino}pyrrolidin-3-yl]-3-nitrobenzenesulfonamide, SULFATE ION | Authors: | Kuhnert, M, Blum, A, Steuber, H, Diederich, W.E. | Deposit date: | 2015-02-22 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C2-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors. J.Med.Chem., 58, 2015
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