5MGB

Crystal Structure of Rat Peroxisomal Multifunctional enzyme Type-1 (RPMFE1) Complexed with Acetoacetyl-CoA and NAD

Replaces:  5AAK

Summary for 5MGB

• Entry DOI: 10.2210/pdb5mgb/pdb
• Descriptor: Peroxisomal bifunctional enzyme, SULFATE ION, ACETOACETYL-COENZYME A, ... (6 entities in total)
• Functional Keywords: oxidoreductase, acetoacetyl-coa, nad+, mfe1, beta-oxidation, fatty acid, crotonase, 3-hydroxyacyl-coa-dehydrogenase
• Biological source: Rattus norvegicus (Rat)
• Cellular location: Peroxisome: P07896
• Total number of polymer chains: 2
• Total formula weight: 165461.21

Authors

Kasaragod, P.,Kiema, T.-R.,Schmitz, W.,Hiltunen, J.K.,Wierenga, R.K. (deposition date: 2016-11-21, release date: 2016-12-21, Last modification date: 2024-01-17)

• Primary citation: Kasaragod, P.,Midekessa, G.B.,Sridhar, S.,Schmitz, W.,Kiema, T.R.,Hiltunen, J.K.,Wierenga, R.K.; Structural enzymology comparisons of multifunctional enzyme, type-1 (MFE1): the flexibility of its dehydrogenase part.; FEBS Open Bio, 7:1830-1842, 2017; PubMed: 29226071; DOI: 10.1002/2211-5463.12337

Experimental method

X-RAY DIFFRACTION (2.8 Å)