4AGS

Leishmania TDR1 - a unique trimeric glutathione transferase

Summary for 4AGS

Entry DOI	10.2210/pdb4ags/pdb
Descriptor	THIOL-DEPENDENT REDUCTASE 1, GLUTATHIONE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	transferase, leishmaniasis, de-gluathionylation
Biological source	LEISHMANIA INFANTUM
Total number of polymer chains	3
Total formula weight	162362.48
Authors	Fyfe, P.K.,Westrop, G.D.,Silva, A.M.,Coombs, G.H.,Hunter, W.N. (deposition date: 2012-01-31, release date: 2012-07-04, Last modification date: 2012-08-01)
Primary citation	Fyfe, P.K.,Westrop, G.D.,Silva, A.M.,Coombs, G.H.,Hunter, W.N. Leishmania Tdr1 Structure, a Unique Trimeric Glutathione Transferase Capable of Deglutathionylation and Antimonial Prodrug Activation. Proc.Natl.Acad.Sci.USA, 109:11693-, 2012 Cited by PubMed: 22753509 DOI: 10.1073/PNAS.1202593109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation